真菌性乳突炎--免疫力低下者的罕见表现

IF 0.6 Q4 SURGERY
Priti S Hajare, Tanubha Goel, Manishaa E V, Elsa Babu, Aditya Achyut Redkar, Akash Rai
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引用次数: 0

摘要

真菌性乳突炎是一种罕见的疾病,通常与宿主免疫缺陷有关。在经过充分的抗菌治疗后仍出现症状的患者中,必须将其视为鉴别诊断。一名 23 岁的女性患者到耳鼻喉科手术室就诊,主诉两年来偶尔出现左耳流脓,伴有瘙痒、疼痛和听力下降。患者未诉耳后肿胀或疼痛。耳镜检查发现左耳鼓膜隆起、充血、不活动。纯音测听显示左耳有 48.33 分贝的中度混合型听力损失,鼓膜测听显示左耳有 B 型曲线。患者接受了探查性鼓室切开术,中耳和鼓室充满了肉芽组织和外观奇特的绿褐色碎屑,疑似耳真菌碎屑。清除中耳病变后,听骨活动度恢复正常,并完成了乳突皮质切除术。对清除出的碎屑进行 KOH 研究,结果显示真菌成分呈阳性。组织病理学检查显示慢性化脓性中耳炎的特征。标本被送去进行真菌培养,分离出曲霉菌。患者开始口服伏立康唑,每天两次,持续两周。术后恢复顺利,患者的听力也有所改善。真菌性乳突炎虽然罕见,但已见报道,通常见于免疫力低下的患者。需要高度怀疑才能早期诊断并进行适当的治疗,尤其是在免疫功能正常的人身上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fungal Oto-Mastoiditis- A Rare Presentation in Immunocompetent Individuals.

Fungal oto-mastoiditis is a rare condition and is often associated with host immunodeficiency. It has to be considered as a differential diagnosis among patients presenting symptoms despite an adequate antibacterial therapy. A 23-year-old female presented to the ENT OPD with complaints of occasional left ear discharge, since 2 years which was associated with itching, pain and reduced hearing. There were no complaints of swelling or pain behind the ear. Otoscopic examination revealed bulging, congested, immobile tympanic membrane in the left ear. Pure tone audiometry revealed 48.33 dB moderate mixed type of hearing loss in the left ear and tympanometry done showed type B curve in the left ear. Patient was taken up for exploratory tympanotomy where middle ear and antrum was filled with granulation tissue and peculiar looking, unusual greenish-brown debris suspicious of fungal otomycotic debris. Ossicular mobility was attained after clearing the disease from the middle ear and cortical mastoidectomy was completed. KOH study of the debris removed was positive for fungal elements as seen. Histopathological examination revealed features suggestive of Chronic suppurative otitis media. Specimen was sent for fungal culture where Aspergillus species was isolated. Patient was started on Voriconazole orally twice a day for 2 weeks. Postoperative period was uneventful and patient's hearing improved. ® Fungal oto-mastoiditis is a rare but reported entity, which is usually seen in immunocompromised patients. A high index of suspicion is required to reach an early diagnosis and administer suitable treatment, especially when it presents in immunocompetent individuals.

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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
226
审稿时长
6-12 weeks
期刊介绍: Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.
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