[治疗创伤的黄金方法。优化院前创伤护理需要哪些血液制品?]

Maximilian Lothar Bamberg, Christian Grasshoff, Jessica Gerstner, Matthias Fabian Boos, Michael Bentele, Tim Viergutz, Johann Fontana, Peter Rosenberger, Robert Wunderlich
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引用次数: 0

摘要

背景:创伤黄金一小时指的是严重受伤后的第一个小时,在这一关键时刻,及时的医疗响应至关重要,但科学界对这一时限的支持并不一致。本研究强调通过针对具体伤情的治疗来优化创伤护理,而不是仅仅关注治疗速度。目的是记录院前创伤救护中需要改进的地方,尤其是血液和凝血产品的使用:在试点研究之后,我们针对德国医生和救援服务人员设计了一份专门的在线调查问卷,以收集他们对一般创伤救护的看法,特别是对院前使用血液和凝血产品的看法。问卷还通过 5 点李克特量表评估了九种特定血液和凝血产品的适当性。对医生(n = 110)和救援服务人员(n = 142)分别计算了每个项目的百分比,并计算了总分,以确定同意或不同意的模式:这项研究的参与人数为 9837 人,其中 371 人初步回答了问卷,252 名来自德国的参与者最终被纳入统计分析。大多数医生(89.1%)和救援服务人员(90.8%)都认为有必要改善院前创伤护理,尤其是通过使用血液和凝血产品。具体来说,60.9% 的医生和 83.8% 的救援人员支持在院前使用这些产品。红细胞浓缩物和纤维蛋白原因可提高大量失血患者的存活率,分别得到76.2%和67.1%的认可;但对其他血液制品的意见不一:这些数据表明,人们愿意改变创伤治疗方法,并确认存在有效的选择。某些产品的使用得到了现有研究的支持,强调了在临床前环境中实际应用这些产品的必要性。在这里,重点从孤立的时间组成部分转移到在优化的时间间隔内提供的护理质量。理想情况下,及时治疗和高质量治疗应相辅相成,充分利用所有可用的治疗资源。这样就可以开发出一种治疗创伤的黄金方法,以优化创伤护理的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[The golden approach to trauma. Which blood products are needed for optimization of prehospital trauma care?]

Background: The golden hour of trauma denotes the critical first hour after severe injury where timely medical response is crucial, although scientific support for this time frame is inconsistent. This study emphasizes optimizing trauma care by tailoring treatment to the specific injury rather than focusing solely on the speed of treatment. The aim is to document the need for improvement in prehospital trauma care, particularly by the use of blood and coagulation products.

Methods: After a pilot study, a purpose-designed online questionnaire targeted at German physicians and rescue service personnel was utilized to collect their views on general trauma care and specifically on the use of blood and coagulation products in prehospital settings. It also assessed the appropriateness of nine specific blood and coagulation products via a 5-point Likert scale. The percentages for each item were calculated for both physicians (n = 110) and rescue service personnel (n = 142) separately as well as an overall score to delineate patterns of agreement or disagreement.

Results: The study reached 9837 individuals, whereby 371 initially answered the questionnaire and 252 participants from Germany were finally included in the statistical analysis. The majority of both physicians (89.1%) and rescue service personnel (90.8%) agreed on the need to improve prehospital trauma care, particularly through the use of blood and coagulation products. Specifically, 60.9% of physicians and 83.8% of rescue personnel supported the prehospital administration of these products. Red blood cell concentrates and fibrinogen were notably endorsed, with 76.2% and 67.1% approval, respectively, for their potential to enhance survival in patients with significant blood loss; however, opinions varied on other blood products.

Conclusion: The data demonstrated a readiness to change the trauma approach and confirmed that effective options are available. The utilization of certain products is supported by existing research, underlining the need for their practical implementation in preclinical settings. Here, the emphasis shifts from the isolated time components to the quality of care delivered in an optimized time interval. Ideally, timely and high-quality care should complement each other, leveraging all available therapeutic resources. This could lead to the development of a golden approach to trauma to optimize outcomes in trauma care.

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