Wei Yang , Dan Zhou , Hui Peng , Huilin Jiang , Weifeng Chen
{"title":"败血症患者体温与 28 天死亡率之间的关系：回顾性观察研究","authors":"Wei Yang , Dan Zhou , Hui Peng , Huilin Jiang , Weifeng Chen","doi":"10.1016/j.medine.2024.08.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>This study explored the association between body temperature and 28-day septic ICU hospital mortality.</div></div><div><h3>Design</h3><div>Retrospective cohort analysis.</div></div><div><h3>Setting</h3><div>208 ICUs in the United States.</div></div><div><h3>Patients or participants</h3><div>Sepsis patients from 2014–2015 eICU Collaborative Research Database.</div></div><div><h3>Interventions</h3><div>Binary logistic regression models, Generalized Additive Model (GAM), Two-Piece Binary Logistic Regression Model.</div></div><div><h3>Main variables of interest</h3><div>Body temperature, 28-day inpatient mortality.</div></div><div><h3>Results</h3><div>Nonlinear relationship observed; hypothermia (≤36.67 ℃) associated with increased mortality (adjusted OR = 0.74, 95% CI: 0.70–0.80, p < 0.0001).</div></div><div><h3>Conclusions</h3><div>Hypothermia in sepsis correlates with higher mortality; rewarming's potential benefit warrants further exploration.</div></div>","PeriodicalId":94139,"journal":{"name":"Medicina intensiva","volume":"49 4","pages":"Pages 205-215"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The association between body temperature and 28-day mortality in sepsis patients: A retrospective observational study\",\"authors\":\"Wei Yang , Dan Zhou , Hui Peng , Huilin Jiang , Weifeng Chen\",\"doi\":\"10.1016/j.medine.2024.08.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>This study explored the association between body temperature and 28-day septic ICU hospital mortality.</div></div><div><h3>Design</h3><div>Retrospective cohort analysis.</div></div><div><h3>Setting</h3><div>208 ICUs in the United States.</div></div><div><h3>Patients or participants</h3><div>Sepsis patients from 2014–2015 eICU Collaborative Research Database.</div></div><div><h3>Interventions</h3><div>Binary logistic regression models, Generalized Additive Model (GAM), Two-Piece Binary Logistic Regression Model.</div></div><div><h3>Main variables of interest</h3><div>Body temperature, 28-day inpatient mortality.</div></div><div><h3>Results</h3><div>Nonlinear relationship observed; hypothermia (≤36.67 ℃) associated with increased mortality (adjusted OR = 0.74, 95% CI: 0.70–0.80, p < 0.0001).</div></div><div><h3>Conclusions</h3><div>Hypothermia in sepsis correlates with higher mortality; rewarming's potential benefit warrants further exploration.</div></div>\",\"PeriodicalId\":94139,\"journal\":{\"name\":\"Medicina intensiva\",\"volume\":\"49 4\",\"pages\":\"Pages 205-215\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medicina intensiva\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2173572724002625\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina intensiva","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2173572724002625","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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