Shanshan Wang, Jason Shafrin, Kirk W Kerr, Philipp Schuetz
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Outcomes were evaluated over a 1-year time interval. Clinical outcomes of interest included readmission and mortality rates. Economic value of ONS was quantified using three different metrics: cost per death averted, cost per readmission avoided and direct cost savings resulting from changes in postacute mortality and readmission rates. The economic value of ONS was also measured by gains in quality-adjusted life-years.</p><p><strong>Results: </strong>Compared with patients not receiving ONS after hospital discharge, use of ONS during the postacute phase reduced mortality by 36.3% and readmissions by 11.0%. Reductions in readmissions resulted in annual savings of US$1113 per person. When extrapolating the results to the estimated 1 693 034 hospitalised elderly US adults at risk of malnutrition, the use of ONS after hospital discharge would prevent 67 747 deaths and 116 570 hospital readmissions per year. With the estimated cost of nutritional support at US$175 per patient per month corresponding to two servings ONS per day, the ONS cost per death and readmission avoided was estimated at US$4380 and US$2546, respectively.</p><p><strong>Conclusions: </strong>Postdischarge use of ONS among patients at risk for malnutrition is highly cost-effective with important reductions in mortality and readmission rates.</p>","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Health economic value of postacute oral nutritional supplementation in older adult medical patients at risk for malnutrition: a US-based modelling approach.\",\"authors\":\"Shanshan Wang, Jason Shafrin, Kirk W Kerr, Philipp Schuetz\",\"doi\":\"10.1136/bmjopen-2024-086787\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To estimate the health economic value of postdischarge oral nutrition supplement (ONS) consumption among elderly adults who were malnourished during hospitalisation.</p><p><strong>Design: </strong>A cost-effectiveness model was developed from a US payer perspective based on a recent meta-analysis of randomised trials of nutritional support following hospital discharge and studies of US hospital mortality, readmission rates and costs.</p><p><strong>Participants and setting: </strong>The target population of this study was postacute care US patients aged ≥65 years who were identified as malnourished during hospitalisation.</p><p><strong>Intervention and outcome measures: </strong>A decision-tree model was used to evaluate the impact of postacute care daily consumption of ONS compared with no ONS. 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引用次数: 0
摘要
目的:估算住院期间营养不良的老年人出院后食用口服营养补充剂的健康经济价值:估算住院期间营养不良的老年人出院后服用口服营养补充剂(ONS)的健康经济价值:设计:根据最近对出院后营养支持随机试验的荟萃分析以及对美国医院死亡率、再入院率和成本的研究,从美国支付方的角度建立了一个成本效益模型:本研究的目标人群是年龄≥65 岁、在住院期间被确认为营养不良的美国出院后护理患者:采用决策树模型评估急性期后每日食用 ONS 与不食用 ONS 相比的影响。结果评估的时间间隔为 1 年。相关临床结果包括再入院率和死亡率。ONS 的经济价值采用三种不同的指标进行量化:避免每例死亡的成本、避免每次再入院的成本以及因改变急性期后死亡率和再入院率而节省的直接成本。ONS 的经济价值还通过质量调整生命年的收益来衡量:结果:与出院后未接受 ONS 的患者相比,在急性期后阶段使用 ONS 可使死亡率降低 36.3%,再入院率降低 11.0%。再入院率降低后,每人每年可节省 1113 美元。将这一结果推广到约 1 693 034 名有营养不良风险的住院美国老年人身上,出院后使用 ONS 每年可防止 67 747 人死亡和 116 570 人再次入院。营养支持的成本估计为每位患者每月 175 美元,相当于每天两份 ONS,因此每避免一次死亡和再入院的 ONS 成本估计分别为 4380 美元和 2546 美元:有营养不良风险的患者出院后使用 ONS 极具成本效益,可显著降低死亡率和再入院率。
Health economic value of postacute oral nutritional supplementation in older adult medical patients at risk for malnutrition: a US-based modelling approach.
Objective: To estimate the health economic value of postdischarge oral nutrition supplement (ONS) consumption among elderly adults who were malnourished during hospitalisation.
Design: A cost-effectiveness model was developed from a US payer perspective based on a recent meta-analysis of randomised trials of nutritional support following hospital discharge and studies of US hospital mortality, readmission rates and costs.
Participants and setting: The target population of this study was postacute care US patients aged ≥65 years who were identified as malnourished during hospitalisation.
Intervention and outcome measures: A decision-tree model was used to evaluate the impact of postacute care daily consumption of ONS compared with no ONS. Outcomes were evaluated over a 1-year time interval. Clinical outcomes of interest included readmission and mortality rates. Economic value of ONS was quantified using three different metrics: cost per death averted, cost per readmission avoided and direct cost savings resulting from changes in postacute mortality and readmission rates. The economic value of ONS was also measured by gains in quality-adjusted life-years.
Results: Compared with patients not receiving ONS after hospital discharge, use of ONS during the postacute phase reduced mortality by 36.3% and readmissions by 11.0%. Reductions in readmissions resulted in annual savings of US$1113 per person. When extrapolating the results to the estimated 1 693 034 hospitalised elderly US adults at risk of malnutrition, the use of ONS after hospital discharge would prevent 67 747 deaths and 116 570 hospital readmissions per year. With the estimated cost of nutritional support at US$175 per patient per month corresponding to two servings ONS per day, the ONS cost per death and readmission avoided was estimated at US$4380 and US$2546, respectively.
Conclusions: Postdischarge use of ONS among patients at risk for malnutrition is highly cost-effective with important reductions in mortality and readmission rates.
期刊介绍:
BMJ Open is an online, open access journal, dedicated to publishing medical research from all disciplines and therapeutic areas. The journal publishes all research study types, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Publishing procedures are built around fully open peer review and continuous publication, publishing research online as soon as the article is ready.