肛门癌的病理生理学。

IF 2.4 4区医学 Q3 ONCOLOGY

Surgical Oncology Clinics of North America Pub Date : 2024-10-24 DOI:10.1016/j.soc.2024.07.003

Taja Lozar MD , Evie Carchman MD

引用次数: 0

摘要

肛门癌发病的病理生理学被认为与慢性炎症有关，这可能是感染人类乳头瘤病毒（HPV）或艾滋病病毒（HIV）或炎症性肠病引起炎症的结果。肛门人乳头瘤病毒诱导的癌变与宫颈癌相似，都是通过病毒整合到宿主基因组中，并形成前驱病变，称为肛门上皮内瘤变。HPV-16 和 -18 是与肛门癌相关的最常见的 HPV 基因型。肛门癌发病的其他风险因素包括慢性免疫抑制、性活动和性传播疾病、女性性别、肛门生殖器发育不良病史和吸烟。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Pathophysiology of Anal Cancer

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来源期刊

Surgical Oncology Clinics of North America 医学-外科

CiteScore

3.90

自引率

0.00%

发文量

审稿时长

12 months

期刊介绍： Published four times each year—January, April, July, and October—Surgical Oncology Clinics of North America updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Each issue focuses on a single topic in surgical oncology, including pancreatic cancer, radiation oncology, breast cancer, colorectal cancer, head and neck cancer, palliative care, gene therapy, sarcomas, cancer screening, treatment of colorectal cancer, biliary tract and primary liver tumors, breast cancer, imaging, and more.