主动脉粥样硬化升支搭桥术的后期疗效

IF 3.6 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Brett F Curran, Hartzell V Schaff, Heidi M Connolly, Joseph M Dearani, William R Miranda, David S Majdalany, Malakh L Shrestha
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引用次数: 0

摘要

背景:升主动脉至降主动脉搭桥术是复杂主动脉闭塞患者的一种修复选择。据报道,这种技术的早期发病率和死亡率极低,但其长期效果尚不清楚:我们分析了1985年1月至2012年12月期间通过胸骨正中切口接受升主动脉至降主动脉分流术的81例连续性主动脉闭塞患者的后期效果。研究仅限于此时间段,以便进行至少10年的随访。52名患者在之前的修补术后复发了动脉粥样硬化,44名患者在进行升主动脉至降主动脉搭桥术时同时进行了心脏手术:围手术期无死亡病例,5年、10年和20年的总存活率分别为94%、90%和85%,与年龄和性别匹配的人群相似。在随访期间,没有对升-降搭桥术进行干预,也没有发现与搭桥术有关的死亡病例。7名患者(9%)通过胸骨正中切口进行了后续心脏手术,48名患者(59%)的后期成像显示没有血流动力学意义上的狭窄或假性动脉瘤。在后期随访中,收缩压中位数为124毫米汞柱,半数患者未服用或仅服用一种降压药:升主动脉至降主动脉搭桥术是一种安全的手术,对患有复杂主动脉闭塞的成年患者具有良好的长期疗效。该手术疗效持久,似乎还能改善全身性高血压。重要的是,升主动脉至降主动脉旁路术不会妨碍通过胸骨正中切口进行的后续手术的安全进行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Late Outcomes of Ascending-to-Descending Bypass for Aortic Coarctation.

Background: Ascending-to-descending aortic bypass is a repair option for patients with complex aortic coarctation. This technique is reported to have minimal early morbidity and mortality, however, the long-term results of the procedure are unknown.

Methods: We analyzed the late outcomes of 81 consecutive patients with aortic coarctation who underwent ascending-to-descending aortic bypass through a median sternotomy from January 1985 to December 2012. The study was limited to this interval to allow for a minimum of 10-year follow-up. Fifty-two patients had recurrent coarctation after previous repair, and 44 patients had concomitant cardiac procedures at the time of ascending-to-descending bypass.

Results: There was no perioperative mortality, and overall survival at 5, 10, and 20 years was 94%, 90%, and 85%, similar to an age and sex-matched population. There were no interventions for the ascending-to-descending bypass during follow-up, and no deaths were known to be related to the bypass graft. Subsequent cardiac operations were performed through a median sternotomy in 7 patients (9%), and late imaging in 48 patients (59%) demonstrated no hemodynamically significant stenoses or pseudoaneurysms. At late follow-up, median systolic blood pressure was 124 mmHg, and half of the patients were on no or only one antihypertensive.

Conclusions: Ascending-to-descending aortic bypass is a safe operation with excellent long-term outcomes for adult patients with complex aortic coarctation. The procedure is durable and appears to improve systemic hypertension. Importantly, ascending-to-descending bypass does not hinder the safe performance of subsequent operations performed through a median sternotomy.

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来源期刊
Annals of Thoracic Surgery
Annals of Thoracic Surgery 医学-呼吸系统
CiteScore
6.40
自引率
13.00%
发文量
1235
审稿时长
42 days
期刊介绍: The mission of The Annals of Thoracic Surgery is to promote scholarship in cardiothoracic surgery patient care, clinical practice, research, education, and policy. As the official journal of two of the largest American associations in its specialty, this leading monthly enjoys outstanding editorial leadership and maintains rigorous selection standards. The Annals of Thoracic Surgery features: • Full-length original articles on clinical advances, current surgical methods, and controversial topics and techniques • New Technology articles • Case reports • "How-to-do-it" features • Reviews of current literature • Supplements on symposia • Commentary pieces and correspondence • CME • Online-only case reports, "how-to-do-its", and images in cardiothoracic surgery. An authoritative, clinically oriented, comprehensive resource, The Annals of Thoracic Surgery is committed to providing a place for all thoracic surgeons to relate experiences which will help improve patient care.
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