实施 AO 脊柱国际指南后的退行性颈椎脊髓病治疗效果:单中心服务评估

IF 2.6 3区 医学 Q2 CLINICAL NEUROLOGY
Jamie Brannigan, Sundar K Vellaiyappan, Oliver D Mowforth, Joseph Magee, Jibin J Francis, Benjamin M Davies, Mark R Kotter
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引用次数: 0

摘要

简介退行性颈椎脊髓病(DCM)是一种由于脊柱退行性病变导致的无症状颈椎脊髓受压综合征。直到最近,人们对哪些患者适合手术治疗或保守治疗仍未达成正式共识。AO 脊柱国际指南的出台就是为了解决这一问题,它以现有的最佳证据为基础。然而,目前还没有关于将其应用于常规临床实践的报道。我们的目的是评估我们脊柱神经外科中心实施 AO 脊柱指南后的手术效果:利用从 259 名患者的电子医疗记录中收集的数据进行了服务评估,评估结果包括 mJOA 评分变化和并发症。最终分析纳入了 193 名患者的数据:术后 3 个月(P < .001)、6 个月(P < .001)和 12 个月(P < .001),mJOA 评分分别平均提高了 1.53 分、1.44 分和 1.92 分。在这些时间间隔内,mJOA 评分的增加大于或等于最小临床重要性差异 (MCID) 的患者比例(人数)分别为 41%(44/107)、34%(33/96)和 43%(49/114)。28名患者(11.7%)出现了术中并发症。BMI与术后mJOA评分变化之间没有关联:我们的结果与最佳实践数据的结果相当,表明遵守国际指南提供的服务可促进 DCM 患者获得有意义的康复。因此,我们的结果为在临床实践中实施 AO 脊柱国际指南提供了支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outcomes for Degenerative Cervical Myelopathy Following Implementation of the AO Spine International Guidelines: A Single-Centre Service Evaluation.

Introduction: Degenerative cervical myelopathy (DCM) is a syndrome of symptomatic cervical spinal cord compression due to degenerative spinal changes. Until recently there was no formal consensus on exactly which patients are suitable for surgical or conservative management. The AO Spine international guidelines were introduced to address this issue, based on the best available current evidence. However, their implementation into routine clinical practice has not yet been reported. The objective was to evaluate surgical outcomes following the implementation of the AO Spine guidelines at our spinal neurosurgical centre.

Methods: A service evaluation was conducted using data collected from electronic healthcare records for 259 patients, with outcomes of interest including change in mJOA score and complications. Data from 193 patients were included in the final analysis.

Results: There was a mean improvement of the mJOA score by 1.53 points, 1.44 point and 1.92 points at post-operative intervals of 3 months (P < .001), 6 months (P < .001) and 12 months (P < .001). The percentage (number) of patients whose increase in mJOA score was greater than or equal to the minimal clinically importance difference (MCID) was 41% (44/107), 34% (33/96) and 43% (49/114) at these respective time intervals. Intraoperative complications occurred in 28 patients (11.7%). No association was found between BMI and postoperative change in mJOA score.

Conclusion: Our results are comparable to those from best practice data and suggest adherence to international guidelines provides a service that promotes meaningful recovery for patients with DCM. Therefore, our results offer support for implementation of the AO Spine international guidelines in clinical practice.

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来源期刊
Global Spine Journal
Global Spine Journal Medicine-Surgery
CiteScore
6.20
自引率
8.30%
发文量
278
审稿时长
8 weeks
期刊介绍: Global Spine Journal (GSJ) is the official scientific publication of AOSpine. A peer-reviewed, open access journal, devoted to the study and treatment of spinal disorders, including diagnosis, operative and non-operative treatment options, surgical techniques, and emerging research and clinical developments.GSJ is indexed in PubMedCentral, SCOPUS, and Emerging Sources Citation Index (ESCI).
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