用于精确乳腺肿瘤分割的多尺度、多任务融合 UNet 模型。

IF 4.9 2区 医学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Shuo Dai , Xueyan Liu , Wei Wei , Xiaoping Yin , Lishan Qiao , Jianing Wang , Yu Zhang , Yan Hou
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引用次数: 0

摘要

背景和目的:乳腺癌是全球女性最常见的癌症类型,也是女性死亡的主要原因。准确解读这些体积小、形态复杂的肿瘤需要大量的专业知识和时间。因此,开发一种乳腺肿瘤分割模型来协助临床医生进行治疗具有重要的现实意义:我们提出了一个名为 MTF-UNet 的多尺度、多任务模型框架。首先,我们有别于使用不同卷积核大小提取多尺度特征的常见方法,而是使用相同卷积核大小、不同卷积次数来获得多尺度、多层次特征。此外,为了更好地整合不同级别和规模的特征,我们提取了一个新的多分支特征融合块(ADF)。这个区块不同于使用通道和空间注意力来融合特征,而是考虑了不同分支之间的融合权重。其次,我们建议使用预测与肿瘤和背景相关的像素数量来辅助分割,这与使用分类任务来辅助分割的传统方法不同:我们在专有的 DCE-MRI 数据集以及两个公共数据集(BUSI 和 Kvasir-SEG)上进行了大量实验。在上述数据集中,我们的模型在各自的测试集上分别取得了 90.4516%、89.8408% 和 92.8431% 的优异 MIoU 分数。此外,我们的消融研究还证明了每个组件的功效,以及我们的辅助预测分支与其他模型的有效整合:通过全面的实验以及与其他算法的比较,我们提出的方法的有效性、适应性和稳健性得到了证明。我们相信,MTF-UNet 在医学图像分割领域的进一步发展潜力巨大。相关代码和数据见 https://github.com/LCUDai/MTF-UNet.git。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A multi-scale, multi-task fusion UNet model for accurate breast tumor segmentation

Background and Objective:

Breast cancer is the most common cancer type among women worldwide and a leading cause of female death. Accurately interpreting these complex tumors, involving small size and morphology, requires a significant amount of expertise and time. Developing a breast tumor segmentation model to assist clinicians in treatment, therefore, holds great practical significance.

Methods:

We propose a multi-scale, multi-task model framework named MTF-UNet. Firstly, we differ from the common approach of using different convolution kernel sizes to extract multi-scale features, and instead use the same convolution kernel size with different numbers of convolutions to obtain multi-scale, multi-level features. Additionally, to better integrate features from different levels and sizes, we extract a new multi-branch feature fusion block (ADF). This block differs from using channel and spatial attention to fuse features, but considers fusion weights between various branches. Secondly, we propose to use the number of pixels predicted to be related to tumors and background to assist segmentation, which is different from the conventional approach of using classification tasks to assist segmentation.

Results:

We conducted extensive experiments on our proprietary DCE-MRI dataset, as well as two public datasets (BUSI and Kvasir-SEG). In the aforementioned datasets, our model achieved excellent MIoU scores of 90.4516%, 89.8408%, and 92.8431% on the respective test sets. Furthermore, our ablation study has demonstrated the efficacy of each component and the effective integration of our auxiliary prediction branch into other models.

Conclusion:

Through comprehensive experiments and comparisons with other algorithms, the effectiveness, adaptability, and robustness of our proposed method have been demonstrated. We believe that MTF-UNet has great potential for further development in the field of medical image segmentation. The relevant code and data can be found at https://github.com/LCUDai/MTF-UNet.git.
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来源期刊
Computer methods and programs in biomedicine
Computer methods and programs in biomedicine 工程技术-工程:生物医学
CiteScore
12.30
自引率
6.60%
发文量
601
审稿时长
135 days
期刊介绍: To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine. Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.
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