提高标准:用于临床应用的 3D 打印混合骨支架的进展:综述。

IF 3.2 4区 医学 Q3 CELL & TISSUE ENGINEERING
Ahsan Riaz Khan, Navdeep Singh Grewal, Zhang Jun, Ferdous M O Tawfiq, Fairouz Tchier, Rana Muhammad Zulqarnain, Hai-Jun Zhang
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引用次数: 0

摘要

创伤和肿瘤造成的骨骼损伤对人类健康构成了重大挑战。因此,目前骨损伤愈合研究的重点是开发三维(3D)支架材料,以促进和增强骨折骨组织的再生。在这种情况下,精心选择材料和制备工艺对于创建高要求的骨组织工程支架至关重要。这样做是为了优化骨折骨骼的再生。本研究全面分析了在开发骨组织创建支架方面的最新科学进展和困难。首先,我们阐明了骨组织自我修复的组成和过程。综述总结了无机和有机材料在骨组织工程支架中的主要用途。此外,我们还全面研究了用于制备骨组织工程支架的主流技术的最新进展。我们还详细研究了每种方法的独特优势。本文深入探讨了临床应用骨组织工程支架的潜在途径和障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Raising the Bar: Progress in 3D-Printed Hybrid Bone Scaffolds for Clinical Applications: A Review.

Damage to bones resulting from trauma and tumors poses a significant challenge to human health. Consequently, current research in bone damage healing centers on developing three-dimensional (3D) scaffolding materials that facilitate and enhance the regeneration of fractured bone tissues. In this context, the careful selection of materials and preparation processes is essential for creating demanding scaffolds for bone tissue engineering. This is done to optimize the regeneration of fractured bones. This study comprehensively analyses the latest scientific advancements and difficulties in developing scaffolds for bone tissue creation. Initially, we clarified the composition and process by which bone tissue repairs itself. The review summarizes the primary uses of materials, both inorganic and organic, in scaffolds for bone tissue engineering. In addition, we present a comprehensive study of the most recent advancements in the mainstream techniques used to prepare scaffolds for bone tissue engineering. We also examine the distinct advantages of each method in great detail. This article thoroughly examines potential paths and obstacles in bone tissue engineering scaffolds for clinical applications.

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来源期刊
Cell Transplantation
Cell Transplantation 生物-细胞与组织工程
CiteScore
6.00
自引率
3.00%
发文量
97
审稿时长
6 months
期刊介绍: Cell Transplantation, The Regenerative Medicine Journal is an open access, peer reviewed journal that is published 12 times annually. Cell Transplantation is a multi-disciplinary forum for publication of articles on cell transplantation and its applications to human diseases. Articles focus on a myriad of topics including the physiological, medical, pre-clinical, tissue engineering, stem cell, and device-oriented aspects of the nervous, endocrine, cardiovascular, and endothelial systems, as well as genetically engineered cells. Cell Transplantation also reports on relevant technological advances, clinical studies, and regulatory considerations related to the implantation of cells into the body in order to provide complete coverage of the field.
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