I. V. Dyachenko, V. D. Dyachenko, P. V. Dorovatovskii, V. N. Khrustalev, V. G. Nenajdenko
{"title":"通过 SNVin 反应三组分合成四氢异喹啉","authors":"I. V. Dyachenko, V. D. Dyachenko, P. V. Dorovatovskii, V. N. Khrustalev, V. G. Nenajdenko","doi":"10.1134/S107042802409001X","DOIUrl":null,"url":null,"abstract":"<p>The three-component reaction of carbocyclic enamino ketones, CH acids, and electrophiles has been studied. Previously unknown 5,6,7,8-tetrahydroisoquinoline derivatives have been synthesized via nucleophilic vinylic substitution (S<sub>N</sub>Vin). The structures of some of the obtained compounds have been determined by X-ray analysis.</p>","PeriodicalId":766,"journal":{"name":"Russian Journal of Organic Chemistry","volume":"60 9","pages":"1619 - 1629"},"PeriodicalIF":0.8000,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Three-Component Synthesis of Tetrahydroisoquinolines via SNVin Reaction\",\"authors\":\"I. V. Dyachenko, V. D. Dyachenko, P. V. Dorovatovskii, V. N. Khrustalev, V. G. Nenajdenko\",\"doi\":\"10.1134/S107042802409001X\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The three-component reaction of carbocyclic enamino ketones, CH acids, and electrophiles has been studied. Previously unknown 5,6,7,8-tetrahydroisoquinoline derivatives have been synthesized via nucleophilic vinylic substitution (S<sub>N</sub>Vin). The structures of some of the obtained compounds have been determined by X-ray analysis.</p>\",\"PeriodicalId\":766,\"journal\":{\"name\":\"Russian Journal of Organic Chemistry\",\"volume\":\"60 9\",\"pages\":\"1619 - 1629\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-11-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Organic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S107042802409001X\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S107042802409001X","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
摘要
研究了碳环烯氨基酮、CH 酸和亲电物的三组分反应。通过亲核乙烯基取代(SNVin)合成了以前未知的 5,6,7,8-四氢异喹啉衍生物。通过 X 射线分析确定了其中一些化合物的结构。
Three-Component Synthesis of Tetrahydroisoquinolines via SNVin Reaction
The three-component reaction of carbocyclic enamino ketones, CH acids, and electrophiles has been studied. Previously unknown 5,6,7,8-tetrahydroisoquinoline derivatives have been synthesized via nucleophilic vinylic substitution (SNVin). The structures of some of the obtained compounds have been determined by X-ray analysis.
期刊介绍:
Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.