通向破裂之路：对微核膜完整性丧失的新认识

IF 14.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Cell Pub Date : 2024-11-07 DOI:10.1016/j.molcel.2024.10.018

Shane M. Harding

引用次数: 0

摘要

马丁等人和迪博纳等人最近在《科学》杂志上发表的两项研究1,2 表明，线粒体产生的活性氧（ROS）驱动了微核膜破裂的机制，对癌症具有重要影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A road to rupture: New insights into the loss of micronuclear membrane integrity

In two recent studies in Science, Martin et al. and Di Bona et al.¹^,² showed that mitochondrial-derived reactive oxygen species (ROS) drive mechanisms responsible for micronuclei membrane rupture, with important implications for cancer.

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来源期刊

Molecular Cell 生物-生化与分子生物学

CiteScore

26.00

自引率

3.80%

发文量

389

审稿时长

1 months

期刊介绍： Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.