使用镧系元素络合物与四氮杂三亚苯基敏化剂的尿酸比率探针的作用机制与评估

IF 7.6 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Chemical Science Pub Date : 2024-11-07 DOI:10.1039/d4sc05743k

Xinyi Wen, Huishan Li, Zhijie Ju, Renren Deng, David Parker

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引用次数: 0

摘要

制备了一系列新配体，这些配体将贫电子芳香族分子（dpqMe2 和 dpqPh2 发色团）结合到基于四氮杂环十二烷或三氮杂环壬烷的络合物结构中、并评估了其 Eu（III）和 Tb（III）配合物的随时间变化的光物理特性，以便对稀释血清溶液中的尿酸盐进行选择性和快速的比率分析，同时利用瞬态吸收光谱对中间复合物的性质和激发态动力学进行了详细的机理研究。

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Mechanism of Action and Evaluation of Ratiometric Probes for Uric Acid Using Lanthanide Complexes with Tetraazatriphenylene Sensitisers

A series of new ligands has been prepared that incorporate electron-poor aromatic moieties (dpqMe₂ and dpqPh₂ chromophores) into tetraazacyclododecane or triazacyclononane based complex structures, and the time-dependent photophysical properties of their Eu(III) and Tb (III) complexes evaluated for the selective and rapid ratiometric analysis of urate in diluted serum solution, together with detailed mechanistic studies probing the nature of the intermediate exciplex and the excited state dynamics using transient absorption spectroscopy.

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来源期刊

Chemical Science CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

14.40

自引率

4.80%

发文量

1352

审稿时长

2.1 months

期刊介绍： Chemical Science is a journal that encompasses various disciplines within the chemical sciences. Its scope includes publishing ground-breaking research with significant implications for its respective field, as well as appealing to a wider audience in related areas. To be considered for publication, articles must showcase innovative and original advances in their field of study and be presented in a manner that is understandable to scientists from diverse backgrounds. However, the journal generally does not publish highly specialized research.