由 1-[2-甲基-4-(甲硫基)喹啉-3-基]丙-2-酮衍生的新型希夫碱的合成与转化

IF 0.8 4区化学 Q4 CHEMISTRY, ORGANIC

Russian Journal of Organic Chemistry Pub Date : 2024-11-06 DOI:10.1134/S1070428024080025

I. L. Aleksanyan, L. P. Hambardzumyan

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引用次数: 0

摘要

从 1-[2-甲基-4-甲硫基喹啉-3-基]丙-2-酮和 1-[2-甲基-4-(甲硫基)喹啉（苯环被取代）]开始，合成了新型希夫碱衍生物。为了得到含有 4-（甲硫基）基团的希夫碱衍生物，先将相应的 4-硫基喹啉-丙-2-酮和 3-（2-氯烯丙基）-4-硫基喹啉甲基化，然后将得到的 3-（2-氯烯丙基）-4-（甲硫基）喹啉中的氯烯丙基进行酸水解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Synthesis and Transformations of Novel Shiff Bases Derived from 1-[2-Methyl-4-(methylsulfanyl)quinolin-3-yl]propan-2-ones

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Synthesis and Transformations of Novel Shiff Bases Derived from 1-[2-Methyl-4-(methylsulfanyl)quinolin-3-yl]propan-2-ones

Novel Schiff base derivatives were synthesized, starting from 1-[2-methyl-4-sulfanylquinolin-3-yl]propan-2-ones and 1-[2-methyl-4-(methylsulfanyl)quinoline, substituted in the benzene ring. To obtain the Schiff base derivatives containing the 4-(methylsulfanyl) group, the corresponding 4-sulfanylquinoline-propan-2-ones and 3-(2-chloroallyl)-4-sulfanylquinolines were methylated, and then the chloroallyl group in the resulting 3-(2-chloroallyl)-4-(methylsulfanyl)quinolines was subjected to acid hydrolysis.

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来源期刊

Russian Journal of Organic Chemistry 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

139

审稿时长

3-6 weeks

期刊介绍： Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.