比较腹腔镜海勒肌切开术和内窥镜球囊扩张术治疗贲门失弛缓症:对生活质量和患者满意度的影响。

Suleyman Atalay, Adem Akçakaya
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引用次数: 0

摘要

背景:Achalasia 是一种罕见的食管神经退行性疾病,会导致食管蠕动功能受损,食管下括约肌(LES)无法放松。这会导致吞咽困难、反胃、胸痛和体重减轻等症状。在各种治疗方法中,腹腔镜海勒肌切开术(LHM)、内镜下球囊扩张术(EBD)和口周内镜下肌切开术(POEM)是常用的方法。本研究旨在比较 LHM 和 EBD 治疗贲门失弛缓症的疗效和长期临床结果:研究回顾了 Bezmialem Vakıf 大学医院的患者病历,纳入了 36 名接受 LHM 和 EBD 治疗的贲门失弛缓症患者。研究人员使用术前艾卡评分(Pre-ES)对患者进行术前评估,使用术后艾卡评分(Post-ES)对患者进行术后评估,并使用弛缓症生活质量(ASQL)问卷和患者满意度评分(PSS)对患者进行评估:接受 LHM 的 19 位患者的平均年龄为(49.37±10.48)岁。接受 EBD 的 17 名患者的平均年龄为(59.24±14.39)岁。围手术期并发症包括 LHM 组的一名患者发生食管粘膜穿孔,三名患者(17.64%)发生出血,EBD 组的一名患者(5.88%)发生食管穿孔。在平均 90 个月的随访中,LHM 组有两名患者(10.53%)出现胃食管反流,EBD 组有八名患者(47%)出现胃食管反流。两组患者的前ES值相似。与 EBD 组相比,LHM 组的术后 EES 明显下降。对 LHM 组和 EBD 组的 ASQL 和 PSS 结果进行分析后得出结论,LHM 在改善生活质量和提供患者满意度方面比 EBD 更有效(P 值:0.001):根据上述研究结果,得出结论认为,与 EBD 相比,LHM 是一种更安全的干预措施,考虑到其并发症风险低、生活质量得到改善且满意度高,应优先考虑 LHM。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of laparoscopic Heller myotomy and endoscopic balloon dilation in the treatment of achalasia: Effects on quality of life and patient satisfaction.

Background: Achalasia is a rare neurodegenerative disease of the esophagus that causes impaired esophageal peristalsis and the inability of the lower esophageal sphincter (LES) to relax. This results in symptoms such as dysphagia, regurgitation, chest pain, and weight loss. Among the treatment options, Laparoscopic Heller Myotomy (LHM), Endoscopic Balloon Dilation (EBD), and Peroral Endoscopic Myotomy (POEM) are commonly used methods. The aim of this study was to compare the efficacy and clinical long-term results of LHM and EBD in treating achalasia.

Methods: Patient records from Bezmialem Vakıf University Hospital were reviewed, and 36 patients diagnosed with achalasia who underwent LHM and EBD were included in the study. Patients were evaluated using the Pre-operative Eckardt Score (Pre-ES) for preoperative evaluation, the Post-operative Eckardt Score (Post-ES) for postoperative evaluation, the Achalasia Specific Quality of Life (ASQL) questionnaire, and the Patient Satisfaction Scoring (PSS).

Results: The mean age of the 19 patients who underwent LHM was 49.37±10.48 years. The mean age of the 17 patients who underwent EBD was 59.24±14.39 years. Perioperative complications included esophageal mucosal perforation in one patient in the LHM group, bleeding in three patients (17.64%), and esophageal perforation in one patient (5.88%) in the EBD group. At a mean follow-up of 90 months, gastroesophageal reflux developed in two patients (10.53%) in the LHM group and eight patients (47%) in the EBD group. The Pre-ES was similar in both groups. The Post-ES significantly decreased in the LHM group compared to the EBD group. When ASQL and PSS results were analyzed between the LHM and EBD groups, it was concluded that LHM was more effective than EBD in improving the quality of life and providing patient satisfaction (p-value: 0.001).

Conclusion: In light of these findings, it was concluded that LHM is a safer intervention compared to EBD and should be prioritized, considering the low risk of complications, improved quality of life, and high level of satisfaction.

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