胆源性急性胰腺炎患者胆囊切除术后 30 天预后的性别差异。

IF 2.7 3区医学 Q1 SURGERY

American journal of surgery Pub Date : 2024-10-21 DOI:10.1016/j.amjsurg.2024.116034

Nicholas Stevens, Ghazi-Abdullah Saroya, Alain Elian, Saad Shebrain

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引用次数: 0

摘要

背景：胆源性急性胰腺炎（BAP）可导致严重的发病率和死亡率。本研究旨在评估性别是否与胆道急性胰腺炎胆囊切除术后 30 天不良预后相关：将 ACS-NSQIP 数据库（2014-2017 年）中诊断为 BAP 并接受胆囊切除术的患者分为两组：男性和女性。采用单变量和多变量分析比较两组患者的人口统计学特征、围手术期数据和 30 天预后。结果：共调查了 4158 名患者（男性 1556 名，女性 2602 名），发现男性的严重发病率和总发病率都明显高于女性。在多变量分析中，男性是严重发病率的独立预测因素。结论：男性性别与胆囊切除术后胆囊切除术患者发病率的增加有关，但男女患者的死亡率没有差异。

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Gender variations in 30-day outcomes following cholecystectomy in patients with biliary acute pancreatitis

Background

Biliary acute pancreatitis (BAP) can be associated with severe morbidity and mortality. This study aims to evaluate whether gender is associated with worse 30-day postoperative outcomes following cholecystectomy for BAP.

Methods

Patients in the ACS-NSQIP database (2014–2017) with a diagnosis of BAP who underwent cholecystectomy were stratified into two groups: male and female. Patients’ demographic characteristics, perioperative data, and 30- day outcomes between the two groups were compared using univariate and multivariable analyses.

Result

4158 (1556 male, 2602 female) patients were examined. Male gender was found to have significantly higher rates of both serious and overall morbidity. On multivariable analysis, male gender was an independent predictor of serious morbidity. No difference in mortality between the two groups was noted.

Conclusion

Male gender is associated with an increased rate of morbidity after cholecystectomy in patients with BAP, however there is no difference in mortality between the male and female genders.

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来源期刊

American journal of surgery 医学-外科

CiteScore

5.00

自引率

6.70%

发文量

570

审稿时长

56 days

期刊介绍： The American Journal of Surgery® is a peer-reviewed journal designed for the general surgeon who performs abdominal, cancer, vascular, head and neck, breast, colorectal, and other forms of surgery. AJS is the official journal of 7 major surgical societies* and publishes their official papers as well as independently submitted clinical studies, editorials, reviews, brief reports, correspondence and book reviews.