对于有症状的膝关节 OA 患者，在常规镇痛治疗的基础上加用口服甲氨蝶呤可减轻 6 个月时的疼痛。

IF 19.6 1区医学 Q1 MEDICINE, GENERAL & INTERNAL

Annals of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-11-05 DOI:10.7326/ANNALS-24-02769-JC

David S Pisetsky

引用次数: 0

摘要

来源引用：Kingsbury SR、Tharmanathan P、Keding A 等：口服甲氨蝶呤减轻膝骨关节炎疼痛：随机安慰剂对照临床试验。Ann Intern Med.2024;177:1145-1156.39074374.

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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In symptomatic knee OA, adding oral methotrexate to usual analgesia reduced pain at 6 mo.

Source citation: Kingsbury SR, Tharmanathan P, Keding A, et al. Pain reduction with oral methotrexate in knee osteoarthritis: a randomized, placebo-controlled clinical trial. Ann Intern Med. 2024;177:1145-1156. 39074374.

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来源期刊

Annals of Internal Medicine 医学-医学：内科

CiteScore

23.90

自引率

1.80%

发文量

1136

审稿时长

3-8 weeks

期刊介绍： Established in 1927 by the American College of Physicians (ACP), Annals of Internal Medicine is the premier internal medicine journal. Annals of Internal Medicine’s mission is to promote excellence in medicine, enable physicians and other health care professionals to be well informed members of the medical community and society, advance standards in the conduct and reporting of medical research, and contribute to improving the health of people worldwide. To achieve this mission, the journal publishes a wide variety of original research, review articles, practice guidelines, and commentary relevant to clinical practice, health care delivery, public health, health care policy, medical education, ethics, and research methodology. In addition, the journal publishes personal narratives that convey the feeling and the art of medicine.