2000-2024 年非洲草药的微生物污染:系统回顾。

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Environmental Health Insights Pub Date : 2024-10-30 eCollection Date: 2024-01-01 DOI:10.1177/11786302241293345
Wisdom K Ahiabor, Samuel Darkwah, Eric S Donkor
{"title":"2000-2024 年非洲草药的微生物污染:系统回顾。","authors":"Wisdom K Ahiabor, Samuel Darkwah, Eric S Donkor","doi":"10.1177/11786302241293345","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Herbal medicine has been a cornerstone of healthcare for centuries, with an estimated 80% of the world's population relying on it. In Africa, herbal medicine is the backbone of rural healthcare, serving 80% to 90% of the population. Despite its widespread use, the safety of herbal medicine raises a significant concern considering the lack of regulation and testing, particularly in Africa. Microbial contamination is a primary safety risk threatening consumer health. In this systematic review, we aimed to synthesise evidence on microbial contamination in herbal medicines across Africa, provide a clear understanding of the problem, and inform effective public health interventions regarding microbial contamination of herbal medicines in Africa.</p><p><strong>Method: </strong>The systematic review was conducted in accordance with the PRISMA guidelines. A literature search was conducted across PubMed, Web of Science, Science Direct, Scopus, and Google Scholar using appropriate search terms. Eligible studies were selected based on predetermined criteria, and data were extracted and analysed.</p><p><strong>Results: </strong>The review included fifty eligible studies in Africa, with a combined sample size of 1996, of which 1791 showed microbial contamination. Bacterial contaminants were reported in 98% of studies, with <i>Escherichia coli</i> (62%) being the most reported bacteria, followed by <i>Staphylococcus aureus</i> (57%), and <i>Bacillus</i> spp. (55%). Fungal contaminants were reported in 70% of studies, with <i>Aspergillus</i> spp. (40%) being the most reported, followed by <i>Penicillium</i> spp. (27%) and <i>Candida</i> spp. (26%). Parasitic contaminants were reported in 2% of the studies reviewed. A total of 70 bacterial species, 37 fungal species, and 6 parasite species were identified in this review.</p><p><strong>Conclusion: </strong>Herbal medicines in Africa pose significant health threats to consumers due to the high prevalence of diverse microbial contaminants and clinically significant pathogens. This emphasises the need for stricter regulations and quality control measures in the production, sale and use of herbal medicines.</p>","PeriodicalId":11827,"journal":{"name":"Environmental Health Insights","volume":"18 ","pages":"11786302241293345"},"PeriodicalIF":2.3000,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528601/pdf/","citationCount":"0","resultStr":"{\"title\":\"Microbial Contamination of Herbal Medicines in Africa, 2000-2024: A Systematic Review.\",\"authors\":\"Wisdom K Ahiabor, Samuel Darkwah, Eric S Donkor\",\"doi\":\"10.1177/11786302241293345\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Herbal medicine has been a cornerstone of healthcare for centuries, with an estimated 80% of the world's population relying on it. In Africa, herbal medicine is the backbone of rural healthcare, serving 80% to 90% of the population. Despite its widespread use, the safety of herbal medicine raises a significant concern considering the lack of regulation and testing, particularly in Africa. Microbial contamination is a primary safety risk threatening consumer health. In this systematic review, we aimed to synthesise evidence on microbial contamination in herbal medicines across Africa, provide a clear understanding of the problem, and inform effective public health interventions regarding microbial contamination of herbal medicines in Africa.</p><p><strong>Method: </strong>The systematic review was conducted in accordance with the PRISMA guidelines. A literature search was conducted across PubMed, Web of Science, Science Direct, Scopus, and Google Scholar using appropriate search terms. Eligible studies were selected based on predetermined criteria, and data were extracted and analysed.</p><p><strong>Results: </strong>The review included fifty eligible studies in Africa, with a combined sample size of 1996, of which 1791 showed microbial contamination. Bacterial contaminants were reported in 98% of studies, with <i>Escherichia coli</i> (62%) being the most reported bacteria, followed by <i>Staphylococcus aureus</i> (57%), and <i>Bacillus</i> spp. (55%). Fungal contaminants were reported in 70% of studies, with <i>Aspergillus</i> spp. (40%) being the most reported, followed by <i>Penicillium</i> spp. (27%) and <i>Candida</i> spp. (26%). Parasitic contaminants were reported in 2% of the studies reviewed. A total of 70 bacterial species, 37 fungal species, and 6 parasite species were identified in this review.</p><p><strong>Conclusion: </strong>Herbal medicines in Africa pose significant health threats to consumers due to the high prevalence of diverse microbial contaminants and clinically significant pathogens. This emphasises the need for stricter regulations and quality control measures in the production, sale and use of herbal medicines.</p>\",\"PeriodicalId\":11827,\"journal\":{\"name\":\"Environmental Health Insights\",\"volume\":\"18 \",\"pages\":\"11786302241293345\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-10-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528601/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Environmental Health Insights\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/11786302241293345\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental Health Insights","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/11786302241293345","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0

摘要

简介几个世纪以来,草药一直是医疗保健的基石,据估计,世界上有 80% 的人口依赖草药。在非洲,草药是农村医疗保健的支柱,为 80% 至 90% 的人口提供服务。尽管草药被广泛使用,但由于缺乏监管和检测,草药的安全性引起了人们的极大关注,尤其是在非洲。微生物污染是威胁消费者健康的主要安全风险。在本系统综述中,我们旨在综合非洲各地草药微生物污染的证据,提供对该问题的清晰认识,并为针对非洲草药微生物污染的有效公共卫生干预措施提供信息:系统性综述按照 PRISMA 指南进行。使用适当的检索词在 PubMed、Web of Science、Science Direct、Scopus 和 Google Scholar 上进行了文献检索。根据预先确定的标准筛选出符合条件的研究,并对数据进行提取和分析:综述包括非洲 50 项符合条件的研究,合计样本量为 1996 个,其中 1791 个样本显示存在微生物污染。98%的研究报告了细菌污染物,报告最多的细菌是大肠杆菌(62%),其次是金黄色葡萄球菌(57%)和芽孢杆菌(55%)。70%的研究报告了真菌污染物,其中报告最多的是曲霉菌属(40%),其次是青霉属(27%)和念珠菌属(26%)。2% 的研究报告了寄生污染物。本综述共发现 70 种细菌、37 种真菌和 6 种寄生虫:结论:非洲的草药对消费者的健康构成了严重威胁,原因是各种微生物污染物和具有临床意义的病原体非常普遍。因此,有必要在草药的生产、销售和使用过程中实施更严格的监管和质量控制措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microbial Contamination of Herbal Medicines in Africa, 2000-2024: A Systematic Review.

Introduction: Herbal medicine has been a cornerstone of healthcare for centuries, with an estimated 80% of the world's population relying on it. In Africa, herbal medicine is the backbone of rural healthcare, serving 80% to 90% of the population. Despite its widespread use, the safety of herbal medicine raises a significant concern considering the lack of regulation and testing, particularly in Africa. Microbial contamination is a primary safety risk threatening consumer health. In this systematic review, we aimed to synthesise evidence on microbial contamination in herbal medicines across Africa, provide a clear understanding of the problem, and inform effective public health interventions regarding microbial contamination of herbal medicines in Africa.

Method: The systematic review was conducted in accordance with the PRISMA guidelines. A literature search was conducted across PubMed, Web of Science, Science Direct, Scopus, and Google Scholar using appropriate search terms. Eligible studies were selected based on predetermined criteria, and data were extracted and analysed.

Results: The review included fifty eligible studies in Africa, with a combined sample size of 1996, of which 1791 showed microbial contamination. Bacterial contaminants were reported in 98% of studies, with Escherichia coli (62%) being the most reported bacteria, followed by Staphylococcus aureus (57%), and Bacillus spp. (55%). Fungal contaminants were reported in 70% of studies, with Aspergillus spp. (40%) being the most reported, followed by Penicillium spp. (27%) and Candida spp. (26%). Parasitic contaminants were reported in 2% of the studies reviewed. A total of 70 bacterial species, 37 fungal species, and 6 parasite species were identified in this review.

Conclusion: Herbal medicines in Africa pose significant health threats to consumers due to the high prevalence of diverse microbial contaminants and clinically significant pathogens. This emphasises the need for stricter regulations and quality control measures in the production, sale and use of herbal medicines.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Environmental Health Insights
Environmental Health Insights PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
3.20
自引率
22.20%
发文量
97
审稿时长
8 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信