非骨水泥模块化股骨假体在股骨头严重缺失和两期髋关节翻修患者中的植入存活率。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI:10.1155/2024/6158822
Sebastian Winther, Naima Elsayed, Karen Dyreborg, Elinborg Mortensen, Michael M Petersen, Jens Stürup, Nikolaj S Winther
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引用次数: 0

摘要

背景和目的:翻修全髋关节置换术(rTHA)是一项具有挑战性的手术,尤其是在骨质严重流失、植入物固定受到影响的情况下。本研究旨在评估一组使用非骨水泥模块化植入物设计的股骨翻修术后复杂患者的植入物存活率、临床效果和中期结果。患者和方法:我们进行了一项回顾性研究,包括使用非骨水泥模块化植入物设计进行翻修性 THA 治疗的 100 名患者(101 个髋关节)。我们将 51 个髋关节鉴定为 Paprosky I-II 型骨缺损,50 个髋关节鉴定为 Paprosky III-IV 型骨缺损。我们审查了手术报告和X光片。患者接受了临床检查以评估哈里斯髋关节评分(HHS),并完成了患者报告结果测量(PROM),包括牛津髋关节评分(OHS)和EQ-5D视觉模拟量表(VAS)。最少随访 2 年(平均 5.8 年;范围 2.0-9.4 年)。结果:在这些病例中,46个髋关节因感染进行了两阶段手术,44个髋关节因无菌性松动进行了翻修。11个髋关节发生了温哥华B2或B3型假体周围骨折。共有5个髋关节需要通过移除股骨假体进行翻修,11名患者出现并发症,导致骨折(1例)、脱位(10例)和软组织翻修(1例)。根据 Kaplan-Meier 生存分析估计,植入物的 5 年存活率为 95%(95%-CI:91%-99%)。所有髋关节都有骨结合的影像学证据,没有一个髋关节下沉超过 5 毫米。此外,80%的患者有股骨近端骨质恢复的影像学证据。平均 HHS 为 78。结论:在复杂的翻修THA病例中,使用模块化翻修股骨系统取得了很好的效果。通过Kaplan-Meier存活率分析估计,植入物的5年存活率为95%(95%-CI:91%-99%),所有髋关节都有骨整合的影像学证据,没有一个髋关节下沉超过5毫米。值得注意的是,80%的人都有股骨近端骨质恢复的影像学证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Implant Survival of an Uncemented Modular Femoral Implant in Patients With Severe Femoral Bone Loss and 2-Stage Hip Revision.

Background and Purpose: Revision total hip arthroplasty (rTHA) is a challenging procedure especially in the presence of severe bone loss where implant fixation is compromised. The aim of this study was to evaluate implant survival, clinical outcome, and midterm results in a group of complex patients after femoral revision using an uncemented modular implant design. Patients and Methods: We performed a retrospective study including 100 patients (101 hips) treated with revision THA using an uncemented modular implant design. We identified 51 hips as Paprosky types I-II and 50 hips as Paprosky III-IV bone defects. We reviewed operative reports and radiographs. Patients underwent a clinical examination to assess the Harris Hip Score (HHS) and completed patient-reported outcome measures (PROM), including the Oxford Hip Score (OHS) and the EQ-5D Visual Analog Scale (VAS). Minimum follow-up was 2 years (average, 5.8 years; range, 2.0-9.4 years). Results: Among the cases, 46 hips were revised for infection in a 2-stage procedure and 44 hips for aseptic loosening. 11 hips had periprosthetic fractures of Vancouver type B2 or B3. A total of 5 hips required revision with removal of the femoral implant and 11 patients experienced complications resulting in fracture (n = 1), dislocation (n = 10), and soft tissue revision (n = 1). The 5-year implant survival estimated by Kaplan-Meier survival analysis was 95% (95%-CI: 91%-99%). All hips had radiographic evidence of osseointegration and no one with subsidence greater than 5 mm. Additionally, 80% showed radiographic evidence of restoration of proximal femoral bone. Mean HHS was 78. Conclusion: In complex cases of revision THA, using a modular revision femoral system yielded promising results. The 5-year implant survival estimated by Kaplan-Meier survival analysis was 95% (95%-CI: 91%-99%), with all hips demonstrating radiographic evidence of osseointegration and no one with subsidence greater than 5 mm. Notably 80% showed radiographic evidence of restoration of proximal femoral bone.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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