加纳 Sunyani 市 24-59 个月儿童的 RTS、S 疟疾疫苗接种;2023 年。

Mansulu Mohammed Zacharia, Sorengmen Amos Ziema, Williams Azumah Abanga, Richard Adinkrah Kyeremeh, Christopher Sunkwa Tamal, Michael Rockson Adjei, Chrysantus Kubio
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引用次数: 0

摘要

背景:RTS,S疟疾疫苗试种成功后,世界卫生组织建议将其用于流行地区儿童恶性疟原虫疟疾的预防。尽管疟疾疫苗的益处已得到证实,但其接种率,尤其是第四剂的接种率仍然相对较低。我们评估了加纳苏亚尼市 24-59 个月儿童对 RTS,S 疟疾疫苗的完全接种率及相关因素:我们对桑亚尼市 361 名 24-59 个月儿童的看护者进行了横断面研究,这些儿童至少接种过一剂 RTS S 型疟疾疫苗。研究人员向照顾者发放了结构化问卷,并从母婴健康记录本中提取了相关的疫苗接种信息。采用二元逻辑回归分析来确定完全接种疫苗的相关因素,置信区间为 95%:结果:约 45% 的儿童(164/361)完成了 RTS S 疟疾疫苗接种计划。年龄在 48-59 个月的儿童(AOR:0.26,95 %CI:0.09-0.76)、照顾者认为儿童被用于实验的儿童(AOR:0.29,95 %CI:0.16-0.54)或怀疑疫苗安全性的儿童(AOR:0.27,95 %CI:0.14-0.52)完成四剂接种的可能性较低。另一方面,报告疫苗短缺和长途跋涉获得免疫服务(AOR:3.15, 95 %CI:1.17-8.47 )以及对疟疾疫苗有充分了解(AOR:1.89, 95 %CI:1.08-3.29 )的照顾者的子女更有可能完成疫苗接种计划:结论:开始接种RTS,S疟疾疫苗的儿童中只有不到一半的人完成了全部接种计划。儿童年龄、看护者对疟疾疫苗的了解和看法以及获得免疫服务的机会与完全接种 RTS S 疟疾疫苗有关。加强对照料者的教育和免疫接种服务可提高后续剂量的接种率和第四剂的覆盖率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
RTS, S malaria vaccination among children aged 24-59 months in the Sunyani Municipality, Ghana; 2023.

Background: Following the successful pilot of RTS,S malaria vaccine, it has been recommended by the WHO for prevention of Plasmodium falciparum malaria in children living in endemic areas. Despite the proven benefits of the malaria vaccine, uptake especially of the fourth dose, remains relatively low. We assessed complete uptake of RTS,S malaria vaccine among children 24-59 months and associated factors in the Sunyani Municipality of Ghana.

Methods: A cross-sectional study was conducted among 361 caregivers of children aged 24-59 months in the Sunyani Municipality, who had received at least one dose of RTS,S malaria vaccine. Structured questionnaires were administered to caregivers and relevant vaccination information was extracted from the maternal and child health record books. Binary logistic regression analysis was used to determine factors associated with complete uptake of the vaccine at 95 % confidence interval (CI).

Results: Approximately 45 % (164/361) of the children had completed the RTS,S malaria vaccination schedule. Children aged 48-59 months (AOR:0.26, 95 %CI:0.09-0.76), those with caregivers who believed that children were being used for experiment (AOR:0.29, 95 %CI:0.16-0.54) or doubted the safety of the vaccine (AOR:0.27, 95 %CI:0.14-0.52) were less likely to complete the four doses. On the other hand, children of caregivers who reported vaccine shortages and travelled long distances to access immunization services (AOR:3.15, 95 %CI:1.17-8.47), and those with adequate knowledge on the malaria vaccine (AOR:1.89, 95 %CI:1.08-3.29) were more likely to complete the vaccination schedule.

Conclusion: Less than half of the children who started RTS,S malaria vaccination completed the full schedule. Age of child, caregiver knowledge and perception of the malaria vaccine, and access to immunization service were associated with complete uptake of the RTS,S malaria vaccine. Strengthening caregiver education and access to immunization services could improve uptake of the subsequent doses and coverage of the fourth dose.

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