{"title":"了解接受家庭医疗护理的老年患者不良用药与跌倒之间的关系:OHCARE 研究。","authors":"Naoko Murakami, Mai Kabayama, Tomoko Yano, Chika Nakamura, Yuka Fukata, Chihiro Morioka, Wen Fang, Yumiko Nako, Yuki Omichi, Eriko Koujiya, Kayo Godai, Michiko Kido, Winston Tseng, Toshinori Nakamura, Atsushi Hirotani, Toshio Fukuda, Michio Tamatani, Yoshinari Okuda, Masashi Ikushima, Yoshichika Baba, Masahiro Nagano, Yukio Nakamura, Hiromi Rakugi, Kei Kamide","doi":"10.1177/23337214241291084","DOIUrl":null,"url":null,"abstract":"<p><p><b>Objective:</b> Previous studies suggest older patients with multiple health conditions and medications may experience adverse interactions, leading to negative outcomes. However, there's limited research on this in older adults receiving home medical care. This study assesses whether polypharmacy is linked to falls or other clinical outcomes. <b>Methods:</b> The study population included 217 participants, aged ≥65 years, receiving home medical care, who consented to participate in the Osaka Home Care Registry (OHCARE) study in Japan. The survey examined the association between polypharmacy and clinical outcomes. We defined \"polypharmacy\" as six or more medications taken regularly. <b>Results:</b> Of the participants, 135 (62.6%) had polypharmacy and were significantly more likely to have hypertension or diabetes. Common medications included those for hypertension, diabetes, and mental disorders. Participants with polypharmacy experienced significantly more falls. Multivariate analysis showed an association between polypharmacy and falls (odds ratio: 2.81, 95% confidence interval [1.34, 5.92]). <b>Conclusion:</b> Even in older patients receiving home health care, the use of six or more medications poses a risk of falls. Careful observations and life support by medical stuffs are necessary to prevent falls in older patients with polypharmacy receiving home medical care.</p>","PeriodicalId":52146,"journal":{"name":"Gerontology and Geriatric Medicine","volume":null,"pages":null},"PeriodicalIF":2.1000,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526307/pdf/","citationCount":"0","resultStr":"{\"title\":\"Understanding the Relationship Between Adverse Medication Use and Falls Among Older Patients Receiving Home Medical Care: OHCARE study.\",\"authors\":\"Naoko Murakami, Mai Kabayama, Tomoko Yano, Chika Nakamura, Yuka Fukata, Chihiro Morioka, Wen Fang, Yumiko Nako, Yuki Omichi, Eriko Koujiya, Kayo Godai, Michiko Kido, Winston Tseng, Toshinori Nakamura, Atsushi Hirotani, Toshio Fukuda, Michio Tamatani, Yoshinari Okuda, Masashi Ikushima, Yoshichika Baba, Masahiro Nagano, Yukio Nakamura, Hiromi Rakugi, Kei Kamide\",\"doi\":\"10.1177/23337214241291084\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Objective:</b> Previous studies suggest older patients with multiple health conditions and medications may experience adverse interactions, leading to negative outcomes. However, there's limited research on this in older adults receiving home medical care. This study assesses whether polypharmacy is linked to falls or other clinical outcomes. <b>Methods:</b> The study population included 217 participants, aged ≥65 years, receiving home medical care, who consented to participate in the Osaka Home Care Registry (OHCARE) study in Japan. The survey examined the association between polypharmacy and clinical outcomes. We defined \\\"polypharmacy\\\" as six or more medications taken regularly. <b>Results:</b> Of the participants, 135 (62.6%) had polypharmacy and were significantly more likely to have hypertension or diabetes. Common medications included those for hypertension, diabetes, and mental disorders. Participants with polypharmacy experienced significantly more falls. Multivariate analysis showed an association between polypharmacy and falls (odds ratio: 2.81, 95% confidence interval [1.34, 5.92]). <b>Conclusion:</b> Even in older patients receiving home health care, the use of six or more medications poses a risk of falls. Careful observations and life support by medical stuffs are necessary to prevent falls in older patients with polypharmacy receiving home medical care.</p>\",\"PeriodicalId\":52146,\"journal\":{\"name\":\"Gerontology and Geriatric Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-10-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526307/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gerontology and Geriatric Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/23337214241291084\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"GERIATRICS & GERONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gerontology and Geriatric Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/23337214241291084","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}
Understanding the Relationship Between Adverse Medication Use and Falls Among Older Patients Receiving Home Medical Care: OHCARE study.
Objective: Previous studies suggest older patients with multiple health conditions and medications may experience adverse interactions, leading to negative outcomes. However, there's limited research on this in older adults receiving home medical care. This study assesses whether polypharmacy is linked to falls or other clinical outcomes. Methods: The study population included 217 participants, aged ≥65 years, receiving home medical care, who consented to participate in the Osaka Home Care Registry (OHCARE) study in Japan. The survey examined the association between polypharmacy and clinical outcomes. We defined "polypharmacy" as six or more medications taken regularly. Results: Of the participants, 135 (62.6%) had polypharmacy and were significantly more likely to have hypertension or diabetes. Common medications included those for hypertension, diabetes, and mental disorders. Participants with polypharmacy experienced significantly more falls. Multivariate analysis showed an association between polypharmacy and falls (odds ratio: 2.81, 95% confidence interval [1.34, 5.92]). Conclusion: Even in older patients receiving home health care, the use of six or more medications poses a risk of falls. Careful observations and life support by medical stuffs are necessary to prevent falls in older patients with polypharmacy receiving home medical care.
期刊介绍:
Gerontology and Geriatric Medicine (GGM) is an interdisciplinary, peer-reviewed open access journal where scholars from a variety of disciplines present their work focusing on the psychological, behavioral, social, and biological aspects of aging, and public health services and research related to aging. The journal addresses a wide variety of topics related to health services research in gerontology and geriatrics. GGM seeks to be one of the world’s premier Open Access outlets for gerontological academic research. As such, GGM does not limit content due to page budgets or thematic significance. Papers will be subjected to rigorous peer review but will be selected solely on the basis of whether the research is sound and deserves publication. By virtue of not restricting papers to a narrow discipline, GGM facilitates the discovery of the connections between papers.