了解接受家庭医疗护理的老年患者不良用药与跌倒之间的关系:OHCARE 研究。

IF 2.1 Q3 GERIATRICS & GERONTOLOGY
Gerontology and Geriatric Medicine Pub Date : 2024-10-29 eCollection Date: 2024-01-01 DOI:10.1177/23337214241291084
Naoko Murakami, Mai Kabayama, Tomoko Yano, Chika Nakamura, Yuka Fukata, Chihiro Morioka, Wen Fang, Yumiko Nako, Yuki Omichi, Eriko Koujiya, Kayo Godai, Michiko Kido, Winston Tseng, Toshinori Nakamura, Atsushi Hirotani, Toshio Fukuda, Michio Tamatani, Yoshinari Okuda, Masashi Ikushima, Yoshichika Baba, Masahiro Nagano, Yukio Nakamura, Hiromi Rakugi, Kei Kamide
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引用次数: 0

摘要

目的:以往的研究表明,患有多种疾病和服用多种药物的老年患者可能会发生不良相互作用,从而导致不良后果。然而,对于接受家庭医疗护理的老年人,这方面的研究还很有限。本研究将评估多重用药是否与跌倒或其他临床结果有关。研究方法研究对象包括217名同意参加日本大阪家庭护理登记(OHCARE)研究的接受家庭医疗护理的≥65岁的参与者。调查研究了多药治疗与临床结果之间的关系。我们将 "多药 "定义为定期服用六种或六种以上的药物。调查结果显示在参与者中,135 人(62.6%)有多重药瘾,其中高血压或糖尿病患者的比例明显更高。常见药物包括治疗高血压、糖尿病和精神疾病的药物。服用多种药物的参与者摔倒的次数明显增多。多变量分析显示,多种药物治疗与跌倒之间存在关联(几率比:2.81,95% 置信区间[1.34, 5.92])。结论即使是接受家庭医疗护理的老年患者,使用六种或六种以上的药物也会带来跌倒的风险。有必要通过医疗人员的仔细观察和生活支持来防止接受家庭医疗护理的使用多种药物的老年患者跌倒。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Understanding the Relationship Between Adverse Medication Use and Falls Among Older Patients Receiving Home Medical Care: OHCARE study.

Objective: Previous studies suggest older patients with multiple health conditions and medications may experience adverse interactions, leading to negative outcomes. However, there's limited research on this in older adults receiving home medical care. This study assesses whether polypharmacy is linked to falls or other clinical outcomes. Methods: The study population included 217 participants, aged ≥65 years, receiving home medical care, who consented to participate in the Osaka Home Care Registry (OHCARE) study in Japan. The survey examined the association between polypharmacy and clinical outcomes. We defined "polypharmacy" as six or more medications taken regularly. Results: Of the participants, 135 (62.6%) had polypharmacy and were significantly more likely to have hypertension or diabetes. Common medications included those for hypertension, diabetes, and mental disorders. Participants with polypharmacy experienced significantly more falls. Multivariate analysis showed an association between polypharmacy and falls (odds ratio: 2.81, 95% confidence interval [1.34, 5.92]). Conclusion: Even in older patients receiving home health care, the use of six or more medications poses a risk of falls. Careful observations and life support by medical stuffs are necessary to prevent falls in older patients with polypharmacy receiving home medical care.

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来源期刊
Gerontology and Geriatric Medicine
Gerontology and Geriatric Medicine Medicine-Geriatrics and Gerontology
CiteScore
2.90
自引率
3.70%
发文量
119
审稿时长
12 weeks
期刊介绍: Gerontology and Geriatric Medicine (GGM) is an interdisciplinary, peer-reviewed open access journal where scholars from a variety of disciplines present their work focusing on the psychological, behavioral, social, and biological aspects of aging, and public health services and research related to aging. The journal addresses a wide variety of topics related to health services research in gerontology and geriatrics. GGM seeks to be one of the world’s premier Open Access outlets for gerontological academic research. As such, GGM does not limit content due to page budgets or thematic significance. Papers will be subjected to rigorous peer review but will be selected solely on the basis of whether the research is sound and deserves publication. By virtue of not restricting papers to a narrow discipline, GGM facilitates the discovery of the connections between papers.
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