转移性乳腺癌脊柱手术后的短期疗效:单中心分析。

IF 1.4 Q2 OTORHINOLARYNGOLOGY
Nicole Iafigliola Gomes, Rômulo Augusto Andrade de Almeida, Andrei Fernandes Joaquim
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引用次数: 0

摘要

背景:乳腺癌检测和治疗方面的进步提高了患者的生存率,但也有越来越多的患者患有脊柱转移。这些手术是姑息性的,但可以改善生活质量(QOL):本研究旨在报告一家医疗机构的乳腺癌患者脊柱转移手术后的疼痛和神经功能状况。并对并发症进行记录:进行了一项回顾性、单中心、单臂研究。研究纳入了连续接受脊柱手术的患者。我们分析了人口统计学、手术、组织病理学和临床数据:结果:共纳入 17 名女性患者。3名患者(17.6%)术前术后均无疼痛(n = 3),6名患者(35.3%)术前术后均有疼痛,8名患者(47.1%)术后无疼痛(P = 0.013)。10名(58.8%)患者术前存在缺陷:3例(30%)术后无改善,7例(70%)术后有改善。6例(35.2%)患者术前没有任何缺陷,也没有恶化(n = 6)。术后的弗兰克尔分类显示,11 名患者(64.7%)术后病情保持稳定,5 名患者(29.4%)病情有所好转。一名患者(5.6%)的体力有所下降。两名患者(11.7%)出现术中并发症:结论:手术明显改善了疼痛,并可能对功能产生积极影响。考虑到并发症发生率较低,手术仍是治疗乳腺癌患者脊柱转移的有效手段,而且可能与改善患者的生活质量有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Short-term outcomes after spinal surgery for metastatic breast cancer: A single-center analysis.

Background: Advances in detection and breast cancer treatment lead to higher survival rates, with more patients living with spine metastases. Those surgeries are palliative; however, they can improve the quality of life (QOL).

Objective: The aim of this study is to report pain and neurological function outcomes after surgery for spinal metastatic disease of breast cancer patients of a single institution. Complications were recorded.

Materials and methods: A retrospective, single-center, single-arm study was performed. Consecutive patients who underwent spinal surgery were included. We analyzed demographic, surgical, histopathological, and clinical data.

Results: Seventeen women were included. Three patients (17.6%) did not present pre- and postoperative pain (n = 3), 6 (35.3%) had pain in both situations, and 8 (47.1%) were pain-free postoperatively (P = 0.013). Ten (58.8%) patients had preoperative deficits: 3 (30%) did not improve and 7 (70%) improved after surgery. Six cases (35.2%) did not present preoperative deficits and did not get worse (n = 6). The Frankel classification after the following time showed that 11 patients (64.7%) remained stable after surgery and 5 patients (29.4%) got better. A single patient (5.6%) had deterioration of strength. Two patients (11.7%) had intraoperative complications.

Conclusions: Pain was significantly improved by surgery, with also a possibly positive effect on functionality. Considering the low complication rates, surgery is still a useful tool in the management of spinal metastases in breast cancer patients and may be related to better QOL.

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来源期刊
CiteScore
1.90
自引率
9.10%
发文量
57
审稿时长
12 weeks
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