胸主动脉血管内修复术中的主动脉扩大覆盖与脊髓缺血无关

George C. Chachati MD , Sarah Yousef MD , James A. Brown MD , Nishant Agrawal , Shwetabh Tarun , Kristian Punu , Derek Serna-Gallegos MD, FACS , Julie Phillippi PhD , Ibrahim Sultan MD
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引用次数: 0

摘要

目的胸腔内血管主动脉修复术(TEVAR)后脊髓缺血(SCI)仍是一种使人衰弱的并发症,10% 的患者会出现这种情况。研究表明,延长主动脉覆盖范围是导致 SCI 的一个风险因素。本研究评估了主动脉长度延长覆盖是否是 SCI 的重要风险因素。方法本研究回顾性分析了 2006 年至 2021 年期间在一家机构成功接受 TEVAR 的 277 例连续患者。患者被分为两组:胸主动脉覆盖范围≥205 mm和<205 mm。方差分析用于比较两组之间的这些变量和相关的主动脉覆盖情况。结果 在成功接受 TEVAR 的 269 例患者中,127 例(47.2%)的主动脉覆盖范围≥205 mm,142 例(52.8%)的主动脉覆盖范围为 <205 mm。胸主动脉覆盖范围≥205 毫米的患者更有可能是吸烟者(P < .01)和既往有中风史者(P < .05)。覆盖范围扩大的患者更有可能在术前接受腰椎引流管(LD)治疗(P < .01)。与标准主动脉覆盖相比,扩大主动脉覆盖与较高的 SCI 风险无关(4.7% vs 4.2%; P = .84)。有无术前 LD 的主动脉扩大覆盖与 SCI 无关(P = .91)。结论扩大主动脉覆盖(与标准方法相比)与较高的 SCI 风险无关;但是,在该人群中,预防性腰椎引流的发生率较高,这可能会减轻 SCI 的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Extended aortic coverage in thoracic aortic endovascular repair is not associated with spinal cord ischemia

Objective

Spinal cord ischemia (SCI) after thoracic endovascular aortic repair (TEVAR) remains a debilitating complication, occurring in 10% of patients. Studies have shown that extended aortic coverage is a risk factor for SCI. This study evaluates whether extended aortic length coverage is a significant risk factor for SCI.

Methods

This study retrospectively reviewed 277 consecutive patients who underwent TEVAR successfully between 2006 and 2021 at a single institution. The patients were classified into 2 groups: ≥205 mm and <205 mm of thoracic aortic coverage. Analysis of variance was used to compare these variables and associated aortic coverage between the 2 groups. Univariable logistical regression was used to compare SCI and associated factors.

Results

Of the 269 patients who underwent successful TEVAR, 127 (47.2%) had ≥205 mm and 142 (52.8%) had <205 mm of aorta coverage. Patients with ≥205 mm of thoracic aorta coverage were more likely to be smokers (P < .01) and to have a history of previous stroke (P < .05). Patients with extended coverage were more likely to receive a preoperative lumbar drain (LD) (P < .01). Extended aortic coverage was not associated with a higher risk of SCI compared to standard aortic coverage (4.7% vs 4.2%; P = .84). Extended aortic coverage with or without a preoperative LD did not have an association with SCI (P = .91). Type II endoleaks were seen more in extended aortic coverage (P < .01).

Conclusions

Extended aortic coverage (compared with the standard approach) was not associated with a higher risk of SCI; however, this may have been mitigated by a higher prevalence of prophylactic lumbar drainage in this population.
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