糖高糖生物学的最新重大突破。

IF 2.9 3区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biochemistry Biochemistry Pub Date : 2024-10-30 DOI:10.1021/acs.biochem.4c00418

Jimin Hu, Duc T Huynh, Michael Boyce

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引用次数: 0

摘要

糖基化在生物化学上非常复杂，在功能上对各种过程和疾病状态至关重要，因此是当代研究的一个充满活力的领域。在这里，我们将重点介绍最近在SARS-CoV-2感染和免疫、癌症生物学和免疫疗法以及新发现的糖基化RNA的糖生物学方面取得的一些显著进展。这些研究共同说明了糖基化在正常生物学中的重要性，以及操纵糖基化对疾病治疗的巨大前景。

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Sugar Highs: Recent Notable Breakthroughs in Glycobiology.

Glycosylation is biochemically complex and functionally critical to a wide range of processes and disease states, making it a vibrant area of contemporary research. Here, we highlight a selection of notable recent advances in the glycobiology of SARS-CoV-2 infection and immunity, cancer biology and immunotherapy, and newly discovered glycosylated RNAs. Together, these studies illustrate the significance of glycosylation in normal biology and the great promise of manipulating glycosylation for therapeutic benefit in disease.

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来源期刊

Biochemistry Biochemistry 生物-生化与分子生物学

CiteScore

5.50

自引率

3.40%

发文量

336

审稿时长

1-2 weeks

期刊介绍： Biochemistry provides an international forum for publishing exceptional, rigorous, high-impact research across all of biological chemistry. This broad scope includes studies on the chemical, physical, mechanistic, and/or structural basis of biological or cell function, and encompasses the fields of chemical biology, synthetic biology, disease biology, cell biology, nucleic acid biology, neuroscience, structural biology, and biophysics. In addition to traditional Research Articles, Biochemistry also publishes Communications, Viewpoints, and Perspectives, as well as From the Bench articles that report new methods of particular interest to the biological chemistry community.