{"title":"心脏移植患者感染期间血液中白细胞介素-2受体水平升高。","authors":"V Stolc, J R Krause","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Increased levels of soluble interleukin-2 (IL-2) receptor were found in plasma of six patients after the heart transplantation. The levels peaked the first week after transplantation and then gradually decreased to normal levels. The moderate episodes of heart transplant rejection did not affect the IL-2 receptor levels in comparison to transplant recipients without the rejection episodes. However, the transplant patients with pneumonia had the IL-2 receptor levels ten times higher than healthy controls. Hence, the IL-2 receptor levels in plasma might be a valuable indicator of the dynamics of the acute infection in heart transplant recipients.</p>","PeriodicalId":77705,"journal":{"name":"Diagnostic and clinical immunology","volume":"5 4","pages":"171-4"},"PeriodicalIF":0.0000,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Interleukin-2 receptor levels are increased in blood of heart transplant patients during infections.\",\"authors\":\"V Stolc, J R Krause\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Increased levels of soluble interleukin-2 (IL-2) receptor were found in plasma of six patients after the heart transplantation. The levels peaked the first week after transplantation and then gradually decreased to normal levels. The moderate episodes of heart transplant rejection did not affect the IL-2 receptor levels in comparison to transplant recipients without the rejection episodes. However, the transplant patients with pneumonia had the IL-2 receptor levels ten times higher than healthy controls. Hence, the IL-2 receptor levels in plasma might be a valuable indicator of the dynamics of the acute infection in heart transplant recipients.</p>\",\"PeriodicalId\":77705,\"journal\":{\"name\":\"Diagnostic and clinical immunology\",\"volume\":\"5 4\",\"pages\":\"171-4\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1987-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diagnostic and clinical immunology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic and clinical immunology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Interleukin-2 receptor levels are increased in blood of heart transplant patients during infections.
Increased levels of soluble interleukin-2 (IL-2) receptor were found in plasma of six patients after the heart transplantation. The levels peaked the first week after transplantation and then gradually decreased to normal levels. The moderate episodes of heart transplant rejection did not affect the IL-2 receptor levels in comparison to transplant recipients without the rejection episodes. However, the transplant patients with pneumonia had the IL-2 receptor levels ten times higher than healthy controls. Hence, the IL-2 receptor levels in plasma might be a valuable indicator of the dynamics of the acute infection in heart transplant recipients.
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