乳腺部分照射中同步综合增强的技术可行性

IF 3.4 Q2 ONCOLOGY

Physics and Imaging in Radiation Oncology Pub Date : 2024-10-01 DOI:10.1016/j.phro.2024.100659

Alex Burton , Tamika Cassar , Christy Glenn , Keelan Byrne

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引用次数: 0

摘要

研究了容积调制弧线疗法（VMAT）用于乳腺部分照射（PBI）和肿瘤床同步综合增强（SIB）的可行性。为 10 名患者制定了四种方案：30Gy/5次分割、26Gy/5次分割加30Gy SIB、40.05Gy/15次分割以及40.05Gy/15次分割加48Gy SIB。与均匀剂量相比，5 次分割组的 SIB 减少了同侧乳房的剂量。与均匀剂量相比，15分次臂中的SIB具有非劣质的一致性。加入SIB不会增加其他风险器官的剂量或计划的复杂性。采用SIB的VMAT PBI在两种分次方案中都是可行的。

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Technical feasibility of delivering a simultaneous integrated boost in partial breast irradiation

Feasibility of volumetric modulated arc therapy (VMAT) for partial breast irradiation (PBI) with simultaneous integrated boost (SIB) to tumour bed was investigated. Four plans were created for 10 patients: 30 Gy/5 fractions, 26 Gy/5 fractions with 30 Gy SIB, 40.05 Gy/15 fractions, and 40.05 Gy/15 fractions with 48 Gy SIB. SIB in the 5 fraction arm had reduced ipsilateral breast dose relative to uniform dose. SIB in the 15 fraction arm had noninferior conformity compared to uniform dose. Addition of SIB did not increase other organ-at-risk doses or plan complexity. VMAT PBI with SIB was feasible for both fractionation regimens.

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来源期刊

Physics and Imaging in Radiation Oncology Physics and Astronomy-Radiation

CiteScore

5.30

自引率

18.90%

发文量

审稿时长

6 weeks