弗莱彻-考克斯途径：临床试验教育的独特视角

IF 2.2 Q3 ONCOLOGY

Advances in Radiation Oncology Pub Date : 2024-09-14 DOI:10.1016/j.adro.2024.101637

Shalini Moningi MD , Shane Stecklein MD, PhD , Sonal Noticewala MD, MAS , Olsi Gjyshi MD , Todd Pezzi MD , David Boyce-Fappiano MD , Prajnan Das MD, MS, MPH , Bruce Minsky MD , Emma B. Holliday MD , Andrew J. Bishop MD , Albert C. Koong MD, PhD , Chelsea C. Pinnix MD, PhD

{"title":"弗莱彻-考克斯途径：临床试验教育的独特视角","authors":"Shalini Moningi MD , Shane Stecklein MD, PhD , Sonal Noticewala MD, MAS , Olsi Gjyshi MD , Todd Pezzi MD , David Boyce-Fappiano MD , Prajnan Das MD, MS, MPH , Bruce Minsky MD , Emma B. Holliday MD , Andrew J. Bishop MD , Albert C. Koong MD, PhD , Chelsea C. Pinnix MD, PhD","doi":"10.1016/j.adro.2024.101637","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><div>There currently are no established formal mentorship and training programs for radiation oncology (RO) trainees to learn trial design, creation, writing, or implementation. There only exists informal training on analyzing clinical trials in RO residency programs. The integration of a longitudinal formal training and mentorship program for clinical trialists—consisting of clinical trial education, design, mentorship, and implementation during the RO residency education—will give residents not only formal teaching in the subject but also strong tools and requisite mentorship in hopes to help them succeed as future academic physicians and leaders in the field of RO.</div></div><div><h3>Methods and Materials</h3><div>We developed a clinical trial training pathway in 2018 at MD Anderson Cancer Center, proposing it as a pilot program. The “Fletcher-Cox Pathway” was accepted with a highly positive response by trainees and is now offered as a standard option to RO trainees at our institution.</div></div><div><h3>Results</h3><div>With the guidance of their principal investigator, residents participating in this pathway design and submit a clinical trial for institutional review board review. In 2019, after implementation of the pilot program, 4 of the incoming 7 residents joined the pathway. The program continues, and the current cohort of trainees have received training in clinical trial design and worked with dedicated mentor(s) regarding clinical trial ideas; their studies are currently accruing patients.</div></div><div><h3>Conclusions</h3><div>This pilot program has been viewed by trainees and mentors as successful; it highlights how a structured approach meets a clear need within RO training. We envision the creation of a national platform to increase access, whereby programs adopt this clinical trialist educational pathway, which ultimately leads to the development of a robust clinical trial community with communal resources. We hope that this not only improves and provides educational initiatives to all trainees but also initiates further collaboration.</div></div>","PeriodicalId":7390,"journal":{"name":"Advances in Radiation Oncology","volume":"9 12","pages":"Article 101637"},"PeriodicalIF":2.2000,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Fletcher-Cox Pathway: A Unique View on Clinical Trial Education\",\"authors\":\"Shalini Moningi MD , Shane Stecklein MD, PhD , Sonal Noticewala MD, MAS , Olsi Gjyshi MD , Todd Pezzi MD , David Boyce-Fappiano MD , Prajnan Das MD, MS, MPH , Bruce Minsky MD , Emma B. Holliday MD , Andrew J. Bishop MD , Albert C. Koong MD, PhD , Chelsea C. Pinnix MD, PhD\",\"doi\":\"10.1016/j.adro.2024.101637\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Purpose</h3><div>There currently are no established formal mentorship and training programs for radiation oncology (RO) trainees to learn trial design, creation, writing, or implementation. There only exists informal training on analyzing clinical trials in RO residency programs. The integration of a longitudinal formal training and mentorship program for clinical trialists—consisting of clinical trial education, design, mentorship, and implementation during the RO residency education—will give residents not only formal teaching in the subject but also strong tools and requisite mentorship in hopes to help them succeed as future academic physicians and leaders in the field of RO.</div></div><div><h3>Methods and Materials</h3><div>We developed a clinical trial training pathway in 2018 at MD Anderson Cancer Center, proposing it as a pilot program. The “Fletcher-Cox Pathway” was accepted with a highly positive response by trainees and is now offered as a standard option to RO trainees at our institution.</div></div><div><h3>Results</h3><div>With the guidance of their principal investigator, residents participating in this pathway design and submit a clinical trial for institutional review board review. In 2019, after implementation of the pilot program, 4 of the incoming 7 residents joined the pathway. The program continues, and the current cohort of trainees have received training in clinical trial design and worked with dedicated mentor(s) regarding clinical trial ideas; their studies are currently accruing patients.</div></div><div><h3>Conclusions</h3><div>This pilot program has been viewed by trainees and mentors as successful; it highlights how a structured approach meets a clear need within RO training. We envision the creation of a national platform to increase access, whereby programs adopt this clinical trialist educational pathway, which ultimately leads to the development of a robust clinical trial community with communal resources. We hope that this not only improves and provides educational initiatives to all trainees but also initiates further collaboration.</div></div>\",\"PeriodicalId\":7390,\"journal\":{\"name\":\"Advances in Radiation Oncology\",\"volume\":\"9 12\",\"pages\":\"Article 101637\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2024-09-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Radiation Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2452109424002008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Radiation Oncology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2452109424002008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

目的目前还没有针对放射肿瘤学（RO）受训人员的正式指导和培训计划，以学习试验的设计、创建、撰写或实施。在放射肿瘤学住院医师培训项目中，只有关于临床试验分析的非正式培训。在放射肿瘤学住院医师教育期间，整合临床试验人员的纵向正式培训和指导计划--包括临床试验教育、设计、指导和实施--将不仅为住院医师提供该学科的正式教学，还将提供强大的工具和必要的指导，希望能帮助他们成功成为未来的学术医生和放射肿瘤学领域的领导者。Fletcher-Cox Pathway "得到了受训者的高度认可，目前已作为标准选项提供给本机构的RO受训者。结果在主要研究者的指导下，参与该路径的住院医师设计并提交一项临床试验供机构审查委员会审查。2019 年，在试点计划实施后，新来的 7 名住院医师中有 4 人加入了这一途径。该计划仍在继续，目前的学员已接受了临床试验设计方面的培训，并与专门的导师就临床试验的想法进行了合作；他们的研究目前正在招募患者。我们设想建立一个全国性的平台来提高普及率，让各项目采用这种临床试验人员教育途径，最终形成一个拥有公共资源的强大临床试验社区。我们希望这不仅能改善并为所有受训人员提供教育机会，还能促进进一步的合作。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The Fletcher-Cox Pathway: A Unique View on Clinical Trial Education

Purpose

There currently are no established formal mentorship and training programs for radiation oncology (RO) trainees to learn trial design, creation, writing, or implementation. There only exists informal training on analyzing clinical trials in RO residency programs. The integration of a longitudinal formal training and mentorship program for clinical trialists—consisting of clinical trial education, design, mentorship, and implementation during the RO residency education—will give residents not only formal teaching in the subject but also strong tools and requisite mentorship in hopes to help them succeed as future academic physicians and leaders in the field of RO.

Methods and Materials

We developed a clinical trial training pathway in 2018 at MD Anderson Cancer Center, proposing it as a pilot program. The “Fletcher-Cox Pathway” was accepted with a highly positive response by trainees and is now offered as a standard option to RO trainees at our institution.

Results

With the guidance of their principal investigator, residents participating in this pathway design and submit a clinical trial for institutional review board review. In 2019, after implementation of the pilot program, 4 of the incoming 7 residents joined the pathway. The program continues, and the current cohort of trainees have received training in clinical trial design and worked with dedicated mentor(s) regarding clinical trial ideas; their studies are currently accruing patients.

Conclusions

This pilot program has been viewed by trainees and mentors as successful; it highlights how a structured approach meets a clear need within RO training. We envision the creation of a national platform to increase access, whereby programs adopt this clinical trialist educational pathway, which ultimately leads to the development of a robust clinical trial community with communal resources. We hope that this not only improves and provides educational initiatives to all trainees but also initiates further collaboration.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Advances in Radiation Oncology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

4.60

自引率

4.30%

发文量

208

审稿时长

98 days

期刊介绍： The purpose of Advances is to provide information for clinicians who use radiation therapy by publishing: Clinical trial reports and reanalyses. Basic science original reports. Manuscripts examining health services research, comparative and cost effectiveness research, and systematic reviews. Case reports documenting unusual problems and solutions. High quality multi and single institutional series, as well as other novel retrospective hypothesis generating series. Timely critical reviews on important topics in radiation oncology, such as side effects. Articles reporting the natural history of disease and patterns of failure, particularly as they relate to treatment volume delineation. Articles on safety and quality in radiation therapy. Essays on clinical experience. Articles on practice transformation in radiation oncology, in particular: Aspects of health policy that may impact the future practice of radiation oncology. How information technology, such as data analytics and systems innovations, will change radiation oncology practice. Articles on imaging as they relate to radiation therapy treatment.