镰状细胞血红蛋白病的知识、态度和实践:印度奥迪沙镰状细胞带病例对照研究。

IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Basanta Kumar Bindhani , Kallur Nava Saraswathy , Jayanta Kumar Nayak , Naorem Kiranmala Devi
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引用次数: 0

摘要

尽管镰状细胞血红蛋白(HbS)在奥里萨邦的发病率很高,但受影响社区对镰状细胞性状(SCT)和镰状细胞病(SCD)的认识和了解仍然很低。这项横断面研究评估了 182 名镰状细胞携带者和 200 名年龄性别与社区匹配的对照者对镰状细胞血红蛋白病的认识、态度和实践(KAP)。病例组和对照组对镰状细胞血红蛋白病的总体了解程度都很低(2.8/10 分)。虽然大多数受访者听说过 SCD(85.71% 对 82%),但很少有人知道 SCT(34.07% 对 27%)。值得注意的是,没有一位参与者知道自己的血红蛋白基因型或携带者状态。只有极少数人了解症状、病因和预防措施。对照组的总体态度得分(4.75/11)略高于病例组(4.55/11),平均得分率为 42.25%。虽然大多数人都认识到定期治疗和儿童筛查的必要性(82.4% 的携带者,90.5% 的对照组),但许多人对婚前筛查的必要性并不确定。两组参与者的总体实践得分都很低(0.4/5),但病例的平均实践得分明显高于对照组(11.01% 对 7.55%)。大多数参与者没有定期进行健康检查或采取预防措施(97.25%)。他们通常依靠传统的保健方法进行治疗。参与者表示,缺乏对小儿麻痹症的认识以及害怕歧视、社会孤立和拒绝婚姻是参加筛查的主要障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Knowledge, attitudes, and practices of sickle cell hemoglobinopathies: A case-control study from the sickle cell belt of Odisha, India
Despite the high prevalence of sickle cell haemoglobin (HbS) in Odisha, awareness and understanding of sickle cell trait (SCT) and sickle cell disease (SCD) remain low in affected communities. This cross-sectional study assesses the knowledge, attitude, and practice (KAP) regarding sickle cell hemoglobinopathies among 182 sickle cell carriers and 200 age-sex-community matched controls. The overall knowledge of sickle cell hemoglobinopathies was very low among both case and control groups (score 2.8/10). Although most respondents had heard about SCD (85.71% vs. 82%), few were aware of SCT (34.07% vs. 27%). Notably, none of the participants knew their haemoglobin genotype or carrier status. Only a very small proportion were aware of symptoms, causes, and preventive measures. The overall attitude score was marginally higher in the control group (4.75/11) than in the case group (4.55/11), with an average score of 42.25%. While most recognized the need for regular treatment and screening of children (82.4% carriers, 90.5% controls), many were undecided about the necessity of premarital screening. The overall practice score was very low in both groups (0.4/5), but the mean practice score was significantly higher in cases than controls (11.01% vs. 7.55%). Most participants did not undergo regular health check-ups or engage in preventive measures (97.25%). Traditional health practices were commonly relied upon for treatment. Participants reported a lack of awareness about SCT and fear of discrimination, social isolation, and marriage refusal as major barriers to screening participation.
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来源期刊
CiteScore
4.80
自引率
3.00%
发文量
139
审稿时长
98 days
期刊介绍: Journal of the National Medical Association, the official journal of the National Medical Association, is a peer-reviewed publication whose purpose is to address medical care disparities of persons of African descent. The Journal of the National Medical Association is focused on specialized clinical research activities related to the health problems of African Americans and other minority groups. Special emphasis is placed on the application of medical science to improve the healthcare of underserved populations both in the United States and abroad. The Journal has the following objectives: (1) to expand the base of original peer-reviewed literature and the quality of that research on the topic of minority health; (2) to provide greater dissemination of this research; (3) to offer appropriate and timely recognition of the significant contributions of physicians who serve these populations; and (4) to promote engagement by member and non-member physicians in the overall goals and objectives of the National Medical Association.
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