平价医疗法案》下的医疗补助扩展对全美艾滋病护理连续性结果的影响。

Health affairs scholar Pub Date : 2024-10-07 eCollection Date: 2024-10-01 DOI:10.1093/haschl/qxae128
Peter F Rebeiro, Julia C Thome, Stephen J Gange, Keri N Althoff, Stephen A Berry, Michael A Horberg, Richard D Moore, Michael J Silverberg, Daniel E Sack, Timothy R Sterling, Pedro Sant'Anna, Bryan E Shepherd
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引用次数: 0

摘要

在 HIV 感染者(PWH)中,人们注意到了因医疗保险状况不同而导致的 HIV 治疗结果差异。因此,我们研究了美国各州医疗补助扩展与艾滋病结果之间的关联。2012-2017年期间,在NA-ACCORD临床队列中就诊≥1次的成人(≥18岁)在首次就诊和最后一次就诊或死亡之间每年贡献个人时间;在每个日历年中,临床保留率为≥2次完成的就诊间隔>90天,接受抗逆转录病毒疗法(ART)为接受≥3种抗逆转录病毒药物,病毒抑制为最后一次测定的HIV-1 RNA < 200 copies/mL。入组时的 CD4 是在入组后 6 个月内获得的。差分(DID)模型量化了医疗补助扩展变化(按居住州划分)与艾滋病结果之间的关联。在 50 个州中,有 87 290 名艾滋病感染者接受了 325 113 人年的随访。医疗补助计划的扩大对入院时的 CD4 有很大的积极影响(DID = 93.5,95% CI:52.9, 134 cells/mm3),对临床保留比例有很小的消极影响(DID = -0.19,95% CI:-0.037, -0.01),对接受抗逆转录病毒疗法(DID = 0.001,95% CI:-0.003, 0.005)或病毒抑制(DID = -0.14,95% CI:-0.34, 0.07)没有影响。扩大医疗补助计划对入院时的 CD4 有积极影响,这表明 HIV 检测和护理联系更加及时,但对下游 HIV 护理连续性措施的影响一般为零。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The impact of Medicaid expansion under the Affordable Care Act on HIV care continuum outcomes across the United States.

HIV care continuum outcome disparities by health insurance status have been noted among people with HIV (PWH). We therefore examined associations between state Medicaid expansion and HIV outcomes in the United States. Adults (≥18 years) with ≥1 visit in NA-ACCORD clinical cohorts from 2012-2017 contributed person-time annually between first and final visit or death; in each calendar year, clinical retention was ≥2 completed visits > 90 days apart, antiretroviral therapy (ART) receipt was receipt of ≥3 antiretroviral agents, and viral suppression was last measured HIV-1 RNA < 200 copies/mL. CD4 at enrollment was obtained within 6 months of enrollment in cohort. Difference-in-difference (DID) models quantified associations between Medicaid expansion changes (by state of residence) and HIV outcomes. Across 50 states, 87 290 PWH contributed 325 113 person-years of follow-up. Medicaid expansion had a substantial positive effect on CD4 at enrollment (DID = 93.5, 95% CI: 52.9, 134 cells/mm3), a small negative effect on proportions clinically retained (DID = -0.19, 95% CI: -0.037, -0.01), and no effects on ART receipt (DID = 0.001, 95% CI: -0.003, 0.005) or viral suppression (DID = -0.14, 95% CI: -0.34, 0.07). Medicaid expansion had a positive effect on CD4 at entry, suggesting more timely HIV testing and care linkage, but generally null effects on downstream HIV care continuum measures.

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