西尼斯特综合征左侧肱脑静脉压迫及其神经系统表现。

IF 3.2 Q2 CLINICAL NEUROLOGY
Karthikeyan M Arcot, Vincent S DeOrchis
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引用次数: 0

摘要

胚胎学上,左侧肱静脉(LBV)起源于左右心前静脉之间的吻合通道。这使得左侧肱静脉位于前方的胸骨下动脉和后方的腹股沟动脉之间。这种主动脉与枸杞子静脉相邻的模式是哺乳动物所独有的,是进化过程中的一个怪异现象。随着年龄的增长,升主动脉会展开、拉长和扩张。与此同时,胸廓的几何形状也发生了变化,主要是椎间盘高度下降和脊柱后凸导致胸腔容积减少。这些变化会逐渐压缩枸杞叶。通常情况下,这种压迫会通过侧支通道和 "血液找到一种方法 "来规避。然而,穿越这些迂回路径是有代价的,可能导致转运时间延迟和静脉充血。在侧支通道充足的情况下,压迫枸橼酸静脉可能不会引发任何病理后遗症,但我们提出了一种现象,即在侧支循环不足的情况下,这种压迫可能会导致病理静脉充血。这种解剖异常及其相关的临床特征如果被发现,将为迄今为止无法解释的一些神经系统疾病的治疗方案提供新的途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Syndrome Sinistre: Left Brachiocephalic Vein Compression and its Neurological Manifestations.

Embryologically, the left brachiocephalic vein (LBV) originates as an anastomotic channel between the right and left anterior cardinal veins. This positions the LBV between the manubrium sterni anteriorly and the innominate artery posteriorly. This pattern of adjacency of the aorta to the LBV is unique to mammals and results from a quirk of evolution. With age, the ascending aorta unfolds, elongates and dilates. Simultaneously, there is a change in the thoracic geometry that reduces the thoracic volume primarily from disc height loss and kyphosis. These transitions progressively compress the LBV. Normally, this compression is circumvented via collateral pathways and "Blood finds a way". However, traversing these circuitous pathways comes at a cost and can result in delayed transit times and venous congestion. While it is possible that compression of the LBV in the setting of adequate collateral channels may fail to provoke any pathologic sequelae, we propose a phenomenon in which such compression in the setting of inadequate collateral circulation may lead to a state of pathologic venous congestion. This anatomic anomaly and its associated clinical features, if identified, can offer a new avenue for treatment options for some of the hitherto unexplained neurologic disorders.

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来源期刊
Neurology International
Neurology International CLINICAL NEUROLOGY-
CiteScore
3.70
自引率
3.30%
发文量
69
审稿时长
11 weeks
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