多发性硬化症女性患者的炎性阴道炎：B 细胞清除疗法与其他疾病调节疗法的回顾性分析。

IF 2.9 3区医学 Q2 CLINICAL NEUROLOGY

Multiple sclerosis and related disorders Pub Date : 2024-10-17 DOI:10.1016/j.msard.2024.105921

Sarah Conway , Cory Dodson , Gavin Hui , C. William Pike , Kristin Galetta

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引用次数: 0

摘要

本研究调查了多发性硬化症（wwMS）女性患者在接受B细胞耗竭疗法与其他疾病改变疗法（DMT）治疗时发生炎性阴道炎的情况。对斯坦福大学 2015-2023 年间的医疗记录进行的回顾性分析显示，两组患者的阴道炎发病率相似，表明与 B 细胞疗法无明显关联。尽管如此，炎症性阴道炎在两组治疗者中仍然普遍存在，值得进一步研究其发病机制和治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Inflammatory vaginitis in women with multiple sclerosis: a retrospective analysis of B-cell depleting therapy compared to other disease modifying therapies

This study investigates the occurrence of inflammatory vaginitis in women with Multiple Sclerosis (wwMS) undergoing B-cell depleting therapy versus other disease-modifying therapies (DMTs). Retrospective analysis of medical records from Stanford University between 2015–2023 shows similar rates of vaginitis in both groups, suggesting no significant association with B-cell therapy. Despite this, inflammatory vaginitis remains prevalent in both treatment groups, warranting further investigation into its mechanisms and management.

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来源期刊

Multiple sclerosis and related disorders CLINICAL NEUROLOGY-

CiteScore

5.80

自引率

20.00%

发文量

814

审稿时长

66 days

期刊介绍： Multiple Sclerosis is an area of ever expanding research and escalating publications. Multiple Sclerosis and Related Disorders is a wide ranging international journal supported by key researchers from all neuroscience domains that focus on MS and associated disease of the central nervous system. The primary aim of this new journal is the rapid publication of high quality original research in the field. Important secondary aims will be timely updates and editorials on important scientific and clinical care advances, controversies in the field, and invited opinion articles from current thought leaders on topical issues. One section of the journal will focus on teaching, written to enhance the practice of community and academic neurologists involved in the care of MS patients. Summaries of key articles written for a lay audience will be provided as an on-line resource. A team of four chief editors is supported by leading section editors who will commission and appraise original and review articles concerning: clinical neurology, neuroimaging, neuropathology, neuroepidemiology, therapeutics, genetics / transcriptomics, experimental models, neuroimmunology, biomarkers, neuropsychology, neurorehabilitation, measurement scales, teaching, neuroethics and lay communication.