一家三级医疗中心的股总动脉开放和血管内治疗方法

IF 3.9 2区 医学 Q1 PERIPHERAL VASCULAR DISEASE
Nicholas Wells, Addiskidan Hundito, McKenzie Tuttle, Dana Alameddine, Edouard Aboian, Isibor Arhuidese, Uwe Fischer, Juan Carlos Perez-Lozada, Raul J Guzman, Cassius Iyad Ochoa Chaar
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引用次数: 0

摘要

目的:股总动脉(CFA)周围动脉疾病(PAD)的血管内治疗仍存在争议。本研究比较了涉及股总动脉的开放性和血管内下肢血运重建术(LER)的围术期和长期疗效:方法:对一家三级医疗中心所有接受下肢血管重建术治疗 PAD 的患者进行了回顾性分析。根据首次涉及 CFA 的 LER 将患者分为开放组和血管内组。对患者特征进行了比较,结果分析的重点是同侧CFA再介入率。多变量回归用于确定CFA血管再通策略与CFA再介入之间的关系。根据适应症进行分层分析:2013-2020年间,共有1954名患者接受了4879例LER(包括所有再介入治疗)。22.9%的患者接受了CFA治疗(N=447/1954),15.0%的LER手术涉及CFA(N=734/4879)。与跛行患者相比,接受CLTI治疗的患者更有可能接受开放式CFA治疗(60.6% vs 42.7%, pConclusion):无论适应症如何,CFA血管内治疗与较高的CFA再介入率相关。CFA动脉内膜剥脱术与较高的围手术期并发症和较长的住院时间有关。了解 CFA 病变的严重程度可以改进患者的选择,以获得最佳治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Open and endovascular treatment of the common femoral artery in a tertiary care center.

Objectives: Endovascular treatment of peripheral arterial disease involving the common femoral artery (CFA) remains controversial. This study compares the perioperative and long-term outcomes of open and endovascular lower extremity revascularization (LER) involving the CFA.

Methods: A retrospective analysis of all patients undergoing LER for peripheral arterial disease in a tertiary care center was performed. Patients were divided into the open or endovascular group based on the first LER that involved the CFA. Patient characteristics were compared, and outcomes analysis focused on the ipsilateral CFA reintervention rate. Multivariable regression was used to determine the association between the CFA revascularization strategy and CFA reintervention. Analysis was stratified based on indication.

Results: A total of 1954 patients underwent 4879 LER (including all reinterventions) between 2013 and 2020. The CFA was treated in 22.9% of patients (n = 447/1954) and 15.0% of LER procedures involved the CFA (n = 734/4879). Patients treated for chronic limb-threatening ischemia (CLTI) were more likely to undergo open CFA treatment compared with patients with claudication (60.6% vs 42.7%; P < .001). Patients treated for CLTI with endovascular therapy were more likely to be male compared with patients treated with open surgery (66.7% vs 51.2%; P = .025). In contrast, patients treated for claudication with endovascular therapy were more likely to have CAD (64.9% vs 50.5%; P = .027) and diabetes (49.3% vs 33.0%; P = .013) compared with open surgery. There was no difference in perioperative amputation or mortality, but patients undergoing CFA endarterectomy were more likely to experience postoperative bleeding in the claudication group as well as wound infections and longer hospital length of stay in both indication groups. On follow-up, patients undergoing endovascular LERs were more likely to require an ipsilateral CFA reintervention for both claudication (35.1% vs 21.0%; P = .019) and CLTI (33.3% vs 20.9%; P = .043) with no difference in major amputation or survival between the groups. Among claudicants, CFA endarterectomy was significantly more likely in patients initially treated with endovascular therapy (conversion to open endarterectomy) compared with patients initially treated with open surgery (redo endarterectomy) (14.9% vs 5.0%; P = .015). Multivariable logistic regression revealed an independent association between endovascular therapy and CFA reintervention for claudication (odds ratio, 2.29; 95% confidence interval, 1.16-4.66) and CLTI (odds ratio, 2.38; 95% confidence interval, 1.18-4.90). Kaplan-Meier analysis showed no difference in major adverse limb event-free survival.

Conclusions: Endovascular treatment of the CFA is associated with a higher reintervention of the CFA regardless of indication. CFA endarterectomy is associated with higher perioperative complications and longer hospital stay. Understanding the severity of CFA disease could improve patient selection for optimal therapy.

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来源期刊
CiteScore
7.70
自引率
18.60%
发文量
1469
审稿时长
54 days
期刊介绍: Journal of Vascular Surgery ® aims to be the premier international journal of medical, endovascular and surgical care of vascular diseases. It is dedicated to the science and art of vascular surgery and aims to improve the management of patients with vascular diseases by publishing relevant papers that report important medical advances, test new hypotheses, and address current controversies. To acheive this goal, the Journal will publish original clinical and laboratory studies, and reports and papers that comment on the social, economic, ethical, legal, and political factors, which relate to these aims. As the official publication of The Society for Vascular Surgery, the Journal will publish, after peer review, selected papers presented at the annual meeting of this organization and affiliated vascular societies, as well as original articles from members and non-members.
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