Sara Moufarrij , Christian Dagher , Olga T. Filippova , Qin Zhou , Alexia Iasonos , Nadeem R. Abu-Rustum , Jennifer J. Mueller , Mario M. Leitao , Jaspreet Sandhu , Bernard Bochner , Jeanne Carter , Dennis S. Chi , Yukio Sonoda
{"title":"骨盆开腹术后按尿路改道类型进行的五年生活质量评估","authors":"Sara Moufarrij , Christian Dagher , Olga T. Filippova , Qin Zhou , Alexia Iasonos , Nadeem R. Abu-Rustum , Jennifer J. Mueller , Mario M. Leitao , Jaspreet Sandhu , Bernard Bochner , Jeanne Carter , Dennis S. Chi , Yukio Sonoda","doi":"10.1016/j.ygyno.2024.10.016","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To determine whether urinary diversion procedures performed at time of pelvic exenteration affect quality of life in patients with recurrent gynecologic malignancies.</div></div><div><h3>Methods</h3><div>We performed a retrospective secondary longitudinal analysis of quality of life according to type of urinary diversion patients received. Participants completed a series of validated questionnaires at various time points. We allocated patients based on urinary diversion type to either the continent group (CD; 29 [55 %]) or noncontinent group (NCD; 24 [45 %]).</div></div><div><h3>Results</h3><div>We noted a significant improvement in global health scores from baseline over time (time <em>p</em> = 0.027). Physical functioning scores showed a statistically significant difference over time (at 24 months: NCD, −4.3 [95 % CI, −14.1 to 5.4]; CD, 0.4 [95 % CI, −7.1 to 7.9]. <em>p</em> < 0.001). Social functioning scores were persistently higher for the CD vs NCD group at all time points but did not differ significantly between the groups at baseline (<em>p</em> = 0.75) or over time within the same group (time <em>p</em> = 0.122). Body image scores significantly decreased (reduced burden) over time for both groups (<em>p</em> = 0.044) and were consistently higher in the NCD vs CD group.</div></div><div><h3>Conclusions</h3><div>Patients experienced a return to their baseline quality of life within a year of surgery. Clinicians should prioritize and improve identifying and discussing postoperative challenges such as changes in physical and social functioning and body image.</div></div>","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":null,"pages":null},"PeriodicalIF":4.5000,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Five-year quality-of-life assessment by urinary diversion type after pelvic Exenterations\",\"authors\":\"Sara Moufarrij , Christian Dagher , Olga T. Filippova , Qin Zhou , Alexia Iasonos , Nadeem R. Abu-Rustum , Jennifer J. Mueller , Mario M. Leitao , Jaspreet Sandhu , Bernard Bochner , Jeanne Carter , Dennis S. Chi , Yukio Sonoda\",\"doi\":\"10.1016/j.ygyno.2024.10.016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>To determine whether urinary diversion procedures performed at time of pelvic exenteration affect quality of life in patients with recurrent gynecologic malignancies.</div></div><div><h3>Methods</h3><div>We performed a retrospective secondary longitudinal analysis of quality of life according to type of urinary diversion patients received. Participants completed a series of validated questionnaires at various time points. We allocated patients based on urinary diversion type to either the continent group (CD; 29 [55 %]) or noncontinent group (NCD; 24 [45 %]).</div></div><div><h3>Results</h3><div>We noted a significant improvement in global health scores from baseline over time (time <em>p</em> = 0.027). Physical functioning scores showed a statistically significant difference over time (at 24 months: NCD, −4.3 [95 % CI, −14.1 to 5.4]; CD, 0.4 [95 % CI, −7.1 to 7.9]. <em>p</em> < 0.001). Social functioning scores were persistently higher for the CD vs NCD group at all time points but did not differ significantly between the groups at baseline (<em>p</em> = 0.75) or over time within the same group (time <em>p</em> = 0.122). Body image scores significantly decreased (reduced burden) over time for both groups (<em>p</em> = 0.044) and were consistently higher in the NCD vs CD group.</div></div><div><h3>Conclusions</h3><div>Patients experienced a return to their baseline quality of life within a year of surgery. Clinicians should prioritize and improve identifying and discussing postoperative challenges such as changes in physical and social functioning and body image.</div></div>\",\"PeriodicalId\":12853,\"journal\":{\"name\":\"Gynecologic oncology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.5000,\"publicationDate\":\"2024-10-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gynecologic oncology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0090825824011661\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gynecologic oncology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0090825824011661","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Five-year quality-of-life assessment by urinary diversion type after pelvic Exenterations
Objective
To determine whether urinary diversion procedures performed at time of pelvic exenteration affect quality of life in patients with recurrent gynecologic malignancies.
Methods
We performed a retrospective secondary longitudinal analysis of quality of life according to type of urinary diversion patients received. Participants completed a series of validated questionnaires at various time points. We allocated patients based on urinary diversion type to either the continent group (CD; 29 [55 %]) or noncontinent group (NCD; 24 [45 %]).
Results
We noted a significant improvement in global health scores from baseline over time (time p = 0.027). Physical functioning scores showed a statistically significant difference over time (at 24 months: NCD, −4.3 [95 % CI, −14.1 to 5.4]; CD, 0.4 [95 % CI, −7.1 to 7.9]. p < 0.001). Social functioning scores were persistently higher for the CD vs NCD group at all time points but did not differ significantly between the groups at baseline (p = 0.75) or over time within the same group (time p = 0.122). Body image scores significantly decreased (reduced burden) over time for both groups (p = 0.044) and were consistently higher in the NCD vs CD group.
Conclusions
Patients experienced a return to their baseline quality of life within a year of surgery. Clinicians should prioritize and improve identifying and discussing postoperative challenges such as changes in physical and social functioning and body image.
期刊介绍:
Gynecologic Oncology, an international journal, is devoted to the publication of clinical and investigative articles that concern tumors of the female reproductive tract. Investigations relating to the etiology, diagnosis, and treatment of female cancers, as well as research from any of the disciplines related to this field of interest, are published.
Research Areas Include:
• Cell and molecular biology
• Chemotherapy
• Cytology
• Endocrinology
• Epidemiology
• Genetics
• Gynecologic surgery
• Immunology
• Pathology
• Radiotherapy