骨盆开腹术后按尿路改道类型进行的五年生活质量评估

IF 4.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY
Sara Moufarrij , Christian Dagher , Olga T. Filippova , Qin Zhou , Alexia Iasonos , Nadeem R. Abu-Rustum , Jennifer J. Mueller , Mario M. Leitao , Jaspreet Sandhu , Bernard Bochner , Jeanne Carter , Dennis S. Chi , Yukio Sonoda
{"title":"骨盆开腹术后按尿路改道类型进行的五年生活质量评估","authors":"Sara Moufarrij ,&nbsp;Christian Dagher ,&nbsp;Olga T. Filippova ,&nbsp;Qin Zhou ,&nbsp;Alexia Iasonos ,&nbsp;Nadeem R. Abu-Rustum ,&nbsp;Jennifer J. Mueller ,&nbsp;Mario M. Leitao ,&nbsp;Jaspreet Sandhu ,&nbsp;Bernard Bochner ,&nbsp;Jeanne Carter ,&nbsp;Dennis S. Chi ,&nbsp;Yukio Sonoda","doi":"10.1016/j.ygyno.2024.10.016","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To determine whether urinary diversion procedures performed at time of pelvic exenteration affect quality of life in patients with recurrent gynecologic malignancies.</div></div><div><h3>Methods</h3><div>We performed a retrospective secondary longitudinal analysis of quality of life according to type of urinary diversion patients received. Participants completed a series of validated questionnaires at various time points. We allocated patients based on urinary diversion type to either the continent group (CD; 29 [55 %]) or noncontinent group (NCD; 24 [45 %]).</div></div><div><h3>Results</h3><div>We noted a significant improvement in global health scores from baseline over time (time <em>p</em> = 0.027). Physical functioning scores showed a statistically significant difference over time (at 24 months: NCD, −4.3 [95 % CI, −14.1 to 5.4]; CD, 0.4 [95 % CI, −7.1 to 7.9]. <em>p</em> &lt; 0.001). Social functioning scores were persistently higher for the CD vs NCD group at all time points but did not differ significantly between the groups at baseline (<em>p</em> = 0.75) or over time within the same group (time <em>p</em> = 0.122). Body image scores significantly decreased (reduced burden) over time for both groups (<em>p</em> = 0.044) and were consistently higher in the NCD vs CD group.</div></div><div><h3>Conclusions</h3><div>Patients experienced a return to their baseline quality of life within a year of surgery. Clinicians should prioritize and improve identifying and discussing postoperative challenges such as changes in physical and social functioning and body image.</div></div>","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":null,"pages":null},"PeriodicalIF":4.5000,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Five-year quality-of-life assessment by urinary diversion type after pelvic Exenterations\",\"authors\":\"Sara Moufarrij ,&nbsp;Christian Dagher ,&nbsp;Olga T. Filippova ,&nbsp;Qin Zhou ,&nbsp;Alexia Iasonos ,&nbsp;Nadeem R. Abu-Rustum ,&nbsp;Jennifer J. Mueller ,&nbsp;Mario M. Leitao ,&nbsp;Jaspreet Sandhu ,&nbsp;Bernard Bochner ,&nbsp;Jeanne Carter ,&nbsp;Dennis S. Chi ,&nbsp;Yukio Sonoda\",\"doi\":\"10.1016/j.ygyno.2024.10.016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>To determine whether urinary diversion procedures performed at time of pelvic exenteration affect quality of life in patients with recurrent gynecologic malignancies.</div></div><div><h3>Methods</h3><div>We performed a retrospective secondary longitudinal analysis of quality of life according to type of urinary diversion patients received. Participants completed a series of validated questionnaires at various time points. We allocated patients based on urinary diversion type to either the continent group (CD; 29 [55 %]) or noncontinent group (NCD; 24 [45 %]).</div></div><div><h3>Results</h3><div>We noted a significant improvement in global health scores from baseline over time (time <em>p</em> = 0.027). Physical functioning scores showed a statistically significant difference over time (at 24 months: NCD, −4.3 [95 % CI, −14.1 to 5.4]; CD, 0.4 [95 % CI, −7.1 to 7.9]. <em>p</em> &lt; 0.001). Social functioning scores were persistently higher for the CD vs NCD group at all time points but did not differ significantly between the groups at baseline (<em>p</em> = 0.75) or over time within the same group (time <em>p</em> = 0.122). Body image scores significantly decreased (reduced burden) over time for both groups (<em>p</em> = 0.044) and were consistently higher in the NCD vs CD group.</div></div><div><h3>Conclusions</h3><div>Patients experienced a return to their baseline quality of life within a year of surgery. Clinicians should prioritize and improve identifying and discussing postoperative challenges such as changes in physical and social functioning and body image.</div></div>\",\"PeriodicalId\":12853,\"journal\":{\"name\":\"Gynecologic oncology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.5000,\"publicationDate\":\"2024-10-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gynecologic oncology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0090825824011661\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gynecologic oncology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0090825824011661","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

目的确定盆腔外切时进行的尿路改道手术是否会影响复发性妇科恶性肿瘤患者的生活质量:我们根据患者接受的尿路转流术类型对其生活质量进行了回顾性二次纵向分析。参与者在不同的时间点填写了一系列经过验证的问卷。我们根据尿路改道类型将患者分配到大便失禁组(CD;29 [55%])或非大便失禁组(NCD;24 [45%]):我们注意到,随着时间的推移,总体健康评分较基线有了明显改善(时间 p = 0.027)。随着时间的推移,身体机能评分出现了统计学上的显著差异(24 个月时,NCD,-4.3 [NCD, -4.3 [NCD, -4.3 [NCD, -4.3 [NCDNCD,-4.3 [95 % CI,-14.1 至 5.4];CD,0.4 [95 % CI,-7.1 至 7.9]:患者在术后一年内的生活质量恢复到了基线水平。临床医生应优先考虑并改进术后挑战的识别和讨论,如身体和社会功能的变化以及身体形象。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Five-year quality-of-life assessment by urinary diversion type after pelvic Exenterations

Objective

To determine whether urinary diversion procedures performed at time of pelvic exenteration affect quality of life in patients with recurrent gynecologic malignancies.

Methods

We performed a retrospective secondary longitudinal analysis of quality of life according to type of urinary diversion patients received. Participants completed a series of validated questionnaires at various time points. We allocated patients based on urinary diversion type to either the continent group (CD; 29 [55 %]) or noncontinent group (NCD; 24 [45 %]).

Results

We noted a significant improvement in global health scores from baseline over time (time p = 0.027). Physical functioning scores showed a statistically significant difference over time (at 24 months: NCD, −4.3 [95 % CI, −14.1 to 5.4]; CD, 0.4 [95 % CI, −7.1 to 7.9]. p < 0.001). Social functioning scores were persistently higher for the CD vs NCD group at all time points but did not differ significantly between the groups at baseline (p = 0.75) or over time within the same group (time p = 0.122). Body image scores significantly decreased (reduced burden) over time for both groups (p = 0.044) and were consistently higher in the NCD vs CD group.

Conclusions

Patients experienced a return to their baseline quality of life within a year of surgery. Clinicians should prioritize and improve identifying and discussing postoperative challenges such as changes in physical and social functioning and body image.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Gynecologic oncology
Gynecologic oncology 医学-妇产科学
CiteScore
8.60
自引率
6.40%
发文量
1062
审稿时长
37 days
期刊介绍: Gynecologic Oncology, an international journal, is devoted to the publication of clinical and investigative articles that concern tumors of the female reproductive tract. Investigations relating to the etiology, diagnosis, and treatment of female cancers, as well as research from any of the disciplines related to this field of interest, are published. Research Areas Include: • Cell and molecular biology • Chemotherapy • Cytology • Endocrinology • Epidemiology • Genetics • Gynecologic surgery • Immunology • Pathology • Radiotherapy
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信