日本肌性水肿昏迷中频繁出现的血清阴性原发性甲状腺功能减退症：三份病例报告及系统回顾

IF 0.9 Q4 ENDOCRINOLOGY & METABOLISM

Case Reports in Endocrinology Pub Date : 2024-10-14 eCollection Date: 2024-01-01 DOI:10.1155/2024/2524019

Yosuke Okuno, Kosuke Mukai, Yuri Tamura, Tomoaki Hayakawa, Atsunori Fukuhara, Iichiro Shimomura

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引用次数: 0

摘要

水肿性昏迷是一种罕见的危及生命的甲状腺功能减退症，表现为神经精神、代谢、呼吸和心血管功能障碍。从 2010 年到 2022 年，我院共收治了三例肌水肿性昏迷患者。虽然这些病例的总体特征与之前的报道相似，但我们注意到所有病例的甲状腺自身抗体均为阴性，其中一例的尸检结果显示为终末期甲状腺炎。在对1999年至2022年的病例进行系统回顾时，我们还注意到，相当一部分肌性水肿昏迷是由血清阴性的原发性甲状腺功能减退症引起的，尤其是在日本。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Frequent Seronegative Primary Hypothyroidism in Myxedema Coma in Japan: Three Case Reports With a Systematic Review.

Myxedema coma is a rare life-threatening form of hypothyroidism that manifests as neuropsychiatric, metabolic, respiratory, and cardiovascular dysfunction. From 2010 to 2022, our hospital managed three cases of myxedema coma. While the overall characteristics of these cases were similar to those in previous reports, we noticed that all cases were negative for thyroid autoantibodies and an autopsy in one of the cases exhibited end-stage thyroiditis. During a systematic review of cases from 1999 to 2022, we also noticed that a significant proportion of myxedema coma was caused by seronegative primary hypothyroidism especially in Japan.

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来源期刊

Case Reports in Endocrinology ENDOCRINOLOGY & METABOLISM-

CiteScore

2.10

自引率

0.00%

发文量

审稿时长

13 weeks