鉴别高血压性心脏病和肥厚性心肌病的左心房应变模式:一种心脏磁共振特征。

Huimin Xu, Wei Deng, Zixiang Pan, Kaixuan Yao, Jinxiu Yang, Zhen Wang, Hui Gao, Hongmin Shu, Ren Zhao, Yongqiang Yu, Yuchi Han, Xiaohu Li
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引用次数: 0

摘要

这两种左心室肥厚性疾病早期形态相似,但临床症状和治疗策略不同。回顾性纳入了 45 名 HHD 患者、85 名 HCM 患者(非阻塞性肥厚型心肌病 [HNCM, n = 45] 和阻塞性肥厚型心肌病 [HOCM, n = 40])和 30 名健康对照组(HC)。通过使用 CVI 42 软件在 CMR-FT 模块的两腔和四腔切面上手动绘制轮廓,确定 LA 容积、应变和应变率。LA 容量参数包括 LA 最大、收缩前和最小容量指数,以及总排空分数、被动排空分数和主动排空分数。根据 LA 应变曲线获得 LA 应变参数,包括总应变(εs)、被动应变(εe)、主动应变(εa)、峰值正应变率(SRs)、早期峰值负应变率(SRe)和晚期峰值负应变率(SRa)。εs(AUC = 0.691,P = 0.006;最佳临界值,25.1%)、εa(AUC = 0.654,P = 0.027;最佳临界值,10.5%)、SRs(AUC = 0.710,P = 0.003;最佳临界值,0.81 1/s)和 SRa(AUC = 0.667,P = 0.016;最佳临界值,-1.30 1/s)在 HHD 和 HNCM 的鉴定中显示出显著差异。所有 LA 应变参数在 HHD 和 HOCM 之间的鉴定中均存在差异(所有 P
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Discrimination of Left Atrial Strain Patterns in Hypertensive Heart Disease and Hypertrophic Cardiomyopathy: a Cardiac Magnetic Resonance Feature.

To assess left atrial (LA) strain parameters using cardiovascular magnetic resonance imaging feature tracking (cardiac MRI-FT) for differentiating hypertensive heart disease (HHD) from hypertrophic cardiomyopathy (HCM), which are two left ventricular hypertrophic diseases that could present with similar morphologies in early stage but differ in clinical symptoms and treatment strategies. 45 patients with HHD, 85 patients with HCM (non-obstructive hypertrophic cardiomyopathy [HNCM, n = 45] and obstructive hypertrophic cardiomyopathy [HOCM, n = 40]) and 30 healthy controls (HC) were retrospectively included. LA volumes, strain, and strain rate were determined by manually contouring on the two- and four-chamber views of the CMR-FT module using CVI 42 software. LA volume parameters including LA maximum, precontraction, and minimum volume index, and total, passive, and active emptying fractions were obtained using the biplane methods. The LA strain parameters, including total strain (εs), passive strain (εe), active strain (εa), peak positive strain rate (SRs), early peak negative strain rate (SRe), and late peak negative strain rate (SRa), were obtained from the LA strain curve. The LA strain and LA strain rate were impaired in both HHD group and HCM group, and they were the most severely impaired in the HOCM group. εs (AUC = 0.691, P = 0.006; the best cutoff value, 25.1%), εa (AUC = 0.654, P = 0.027; the best cutoff value, 10.5%), SRs (AUC = 0.710, P = 0.003; the best cutoff value, 0.81 1/s) and SRa (AUC = 0.667, P = 0.016; the best cutoff value, -1.30 1/s) showed significant differences in the identification between HHD and HNCM. All LA strain parameters were different in the identification between HHD and HOCM (all P < 0.05).LA strain parameters can be helpful for differentiating HHD from HCM, providing valuable insights for diagnosis.

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