针对退行性内侧半月板撕裂,在半月板内和周围注射皮质类固醇并进行结构化物理治疗的存活率和疗效。

IF 2.3 3区 医学 Q2 ORTHOPEDICS
Ahmed Mabrouk, Shintaro Onishi, Christophe Jacquet, Etienne Cavaignac, Daphne Guenoun, Matthieu Ollivier
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引用次数: 0

摘要

背景:内侧半月板退行性撕裂是普通人群中常见的病理现象。最近的随机试验表明,关节镜下半月板部分切除术的疗效并不优于保守治疗。然而,有关联合保守治疗效果的信息却很少:假设:在治疗退行性内侧半月板撕裂时,联合进行半月板内和半月板周围皮质类固醇注射以及结构化物理治疗,可获得较高的无手术和无二次注射存活率:方法:对671例有症状的退行性内侧半月板撕裂患者进行了回顾性研究,这些患者接受了联合的半月板内和半月板周围皮质类固醇注射以及结构化物理治疗。患者在超声波引导下注射了每毫升 20 毫克的曲安奈德,其中半月板内 1.5 毫升,半月板壁 1.5 毫升,半月板周围 2 毫升。对免费手术和第二次免费注射的存活率进行了分析。记录了西安大略和麦克马斯特大学评分(WOMAC)、泰格纳活动评分、患者满意度、重返工作状态和重返工作的平均时间:共纳入了 481 名符合纳入标准的患者。平均年龄为 51.1±7.9 岁。术后五年,同侧膝关节无手术和无二次注射的存活率分别为 83% 和 52%。根据参数风险因素调整存活率的多变量分析表明,只有类固醇注射前的渗出才是治疗失败的独立风险因素。在平均 4 ± 2 年的随访中,WOMAC 疼痛评分提高了 5.2 ± 4.9 分,僵硬评分提高了 2 ± 2 分,功能评分提高了 7.3 ± 7.4 分,总体评分提高了 12.4 ± 12.7 分。此外,Tegner 活动评分的明显改善(All p III)与较差的疗效明显相关;P 结论:对于退行性内侧半月板撕裂,将半月板内和半月板周围注射皮质类固醇和结构化物理治疗相结合,可获得较高的无手术率(83%)和无二次注射率(52%),以及有效的临床疗效和5年的满意度:证据级别:IV;回顾性病例系列
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Survivorship and outcomes of intra- and perimeniscal corticosteroids injections with structured physiotherapy for degenerative medial meniscus tears.

Background: Degenerative medial meniscus tears are a common pathology in the general population. Recent randomized trials demonstrated non-superiority of arthroscopic partial meniscectomy over conservative management. However, there is a paucity of information regarding the outcomes of combined conservative treatments.

Hypothesis: It was hypothesized that combined intra- and perimeniscal corticosteroid injections with structured physiotherapy, for degenerative medial meniscus tears, would result in high surgery-free and second injection-free survivorship.

Methods: A retrospective review of 671 patients with symptomatic degenerative medial meniscus tears, who received intra- and perimeniscal corticosteroids injection combined with structured physiotherapy, was conducted. An ultrasound-guided injection of Triamcinolone Hexacetonide 20 mg/ml comprised; 1.5 ml intra-meniscal,1.5 ml in the meniscal wall, and 2 ml in the peri-meniscal space, was performed. Surgery free- and a second injection free-survivorship were analysed. Western Ontario and Macmaster University scores (WOMAC), Tegner activity scores, patient satisfaction, return-to-work status and average time to return to work were recorded.

Results: A total of 481 patients who met the inclusion criteria were included. The mean age was 51.1 ± 7.9 years. At five years post-procedure, surgery-free, and second injection-free survivorship of the ipsilateral knee was 83%, and 52%, respectively. A multivariate analysis adjusting survival on parametric risk factors identified that only effusion before steroid injection was an independent risk factor of treatment failure. At a mean follow-up of 4 ± 2 years, there was an improvement in WOMAC scores by 5.2 ± 4.9 for pain, by 2 ± 2 for stiffness, by 7.3 ± 7.4 for function, and by 12.4 ± 12.7 for the global scores. Additionally, there was significant improvement in the Tegner activity scores (All p < 0.001). Knee effusion and advanced osteoarthritis (Kellgren-Lawrence > III) were significantly associated with poorer outcomes; p < 0.003 and p < 0.0004, respectively.

Conclusion: A combination of intra- and perimeniscal corticosteroid injections and structured physiotherapy for degenerative medial meniscus tears, results in high surgery-free (83%) and second injection-free (52%) survivorship, as well as, effective clinical outcomes and satisfaction at 5 years.

Level of evidence: IV; Retrospective Case Series.

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来源期刊
CiteScore
5.10
自引率
26.10%
发文量
329
审稿时长
12.5 weeks
期刊介绍: Orthopaedics & Traumatology: Surgery & Research (OTSR) publishes original scientific work in English related to all domains of orthopaedics. Original articles, Reviews, Technical notes and Concise follow-up of a former OTSR study are published in English in electronic form only and indexed in the main international databases.
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