一家三级医院血管外科非老年病人的治疗效果。

IF 1.7 2区 医学 Q3 PERIPHERAL VASCULAR DISEASE
Ahmed Azhar Ali, Tarek Hamwi, Carlota Fernandez Prendes, Laura Sikman, Nikolaos Konstantinou, Jan Stana, Nikolaos Tsilimparis
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引用次数: 0

摘要

导言:随着世界人口的增长和老龄化,非老年患者已成为一个独特的患者群体,他们具有特殊的特征,因此对预后的预测至关重要。我们的目的是在一家三级血管中心调查这一患者群体的具体特征:我们对 2017 年 1 月至 2022 年 12 月期间血管外科转诊或治疗的所有 90 岁及以上连续患者进行了回顾性分析。主要终点是分析非老年患者所需的血管服务类型。其他终点包括根据医疗记录评估研究期间的治疗效果。分析以患者为基础:共有 148 名非长者参与了研究。共有 71 名患者(48%)接受了手术治疗,77 名患者(52%)接受了保守治疗。大多数患者因外周动脉疾病(PAD,56 人,37.8%)和主动脉相关疾病(39 人,26.4%)而转诊。其他病症包括急性肢体缺血(ALI,25 例,16.9%)、颈动脉疾病(12 例,8.1%)、肾脏/透析相关疾病(8 例,5.4%)和其他科室转诊(12 例,5.4%)。27%的病例进行了紧急干预。手术指征包括 PAD 卢瑟福分期 IV、V 和 VI;无症状和破裂的主动脉瘤;ALI 卢瑟福分期 I、IIa 和 IIb;无症状和近乎完全闭塞的无症状颈动脉疾病;以及定期接受血液透析的慢性肾功能衰竭患者的透析相关手术。22名患者(14.9%)出现了围手术期并发症,30天内再介入率为7.4%,30天内死亡率为4.7%。手术患者的总体住院时间中位数为 8 晚:结论:非老年患者在人口中所占的比例越来越大,他们转诊到血管外科的比例也越来越高。经过严格筛选的这部分患者可以获得令人满意的短期治疗效果。接受紧急手术的患者30天死亡率较高。与接受保守治疗的患者相比,接受手术的非老年患者的随访死亡率更高。谨慎选择患者和做好充分准备对提高临床疗效至关重要。对非老年患者治疗效果的进一步研究将使医生能够针对不同患者采取更好的循证方法,因此应予以鼓励:临床影响:这项研究强调了对非老年人血管疾病进行管理的日益增长的需求,并强调不能仅凭年龄就将患者排除在手术干预之外。这项研究通过证明谨慎选择患者可获得可接受的短期疗效,对反对为老年人手术的传统偏见提出了挑战。临床医生应完善风险评估和治疗计划,尤其是在平衡手术和保守治疗方案时。合并症而非年龄是决定患者是否适合手术的关键因素,因此在这一不断扩大的人群中,应鼓励采用更多个性化的循证方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outcomes of Nonagenarian Patients in Vascular Surgery Service in a Tertiary Institution.

Introduction: With the world population growing and aging, nonagenarians have become a distinct patient cohort with specific characteristics that render the prediction of outcomes essential. We aimed to investigate the specific characteristics of this patient's cohort in a tertiary vascular center.

Materials and methods: Retrospective analysis was conducted for all consecutive patients 90 years and above referred or treated in the Department of Vascular Surgery between January 2017 and December 2022 for vascular pathologies. The main endpoint was to analyze the type of vascular services required for nonagenarians. Additional endpoints involved evaluation of treatment outcomes during the study period based on medical records. The analysis was patient-based.

Results: A total of 148 nonagenarians were included in the study. In all, 71 (48%) of the patients underwent surgery, whereas 77 (52%) had conservative treatment. Most of the patients were referred for peripheral arterial (PAD; 56, 37.8%) and aortic-related (39, 26.4%) diseases. Other pathologies encountered involved acute limb ischemia (ALI; 25, 16.9%), carotid diseases (12, 8.1%), renal/dialysis-related consultations (8, 5.4%), and referrals from other departments (12, 5.4%). Urgent interventions were performed in 27% of the cases. Indications for surgery included PAD Rutherford Stages IV, V, and VI; symptomatic and ruptured aortic aneurysms; ALI Rutherford Stages I, IIa, and IIb; symptomatic and near total occlusion asymptomatic carotid disease; and dialysis-related procedures for patients with chronic renal failure on regular hemodialysis. Perioperative complications were experienced in 22 patients (14.9%), the 30-day reintervention rate was 7.4%, and 30-day mortality was 4.7%. The overall length of hospital stay for operated patients was a median of 8 nights.

Conclusion: The proportion of nonagenarians in the population is growing and so is their referral to vascular surgery. Satisfactory short-term treatment outcomes can be achieved in this highly selected cohort of patients. Thirty-day mortality is higher in patients undergoing urgent procedures. Follow-up mortality was higher in the operated nonagenarians as compared with those who were treated conservatively. Careful patient selection and thorough preparation are crucial to enhance clinical outcomes. Further research on therapy outcomes of nonagenarians will enable physicians to make better evidence-based approaches to individual patients and should be encouraged.

Clinical impact: The study highlights the growing need to manage vascular diseases in nonagenarians, emphasizing that age alone should not exclude patients from surgical interventions. By demonstrating acceptable short-term outcomes with careful patient selection, this research challenges the traditional bias against operating on the elderly. Clinicians should refine risk assessment and treatment plans, particularly when balancing surgical and conservative options. Comorbidities, rather than age, are key determinants of patient suitability, encouraging more individualized, evidence-based approaches in this expanding demographic.

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来源期刊
CiteScore
5.30
自引率
15.40%
发文量
203
审稿时长
6-12 weeks
期刊介绍: The Journal of Endovascular Therapy (formerly the Journal of Endovascular Surgery) was established in 1994 as a forum for all physicians, scientists, and allied healthcare professionals who are engaged or interested in peripheral endovascular techniques and technology. An official publication of the International Society of Endovascular Specialists (ISEVS), the Journal of Endovascular Therapy publishes peer-reviewed articles of interest to clinicians and researchers in the field of peripheral endovascular interventions.
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