为放射治疗规划建立硅胶乳房植入物模型。

IF 1.1 4区 医学 Q4 ONCOLOGY
Joshua Kirby, Nick West
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引用次数: 0

摘要

目前还没有关于硅胶乳房植入体在中压能量光子束中衰减特性的公开研究。由于体内剂量测定结果存在系统性偏差,本报告研究了 CT Hounsfield 单位与电子密度曲线是否能准确估计硅胶乳房植入体的衰减。以 WT1 块顶部为中心对硅胶乳房植入体进行了 CT 扫描,并创建了简单的 6 MV 和 10 MV 计划。利用 CT 和塌锥算法计算剂量。预测剂量与电离室在植入物下游两点测得的剂量进行比较。治疗计划系统的预测剂量比测量值低 0.9-1.7%。在所有能量和测量深度下,使用水(1 克/立方厘米)对植入体进行密度覆盖可将两者的一致性提高到 1%以下。我们的结论是,对硅胶乳房植入物使用 CT Hounsfield 单位会导致中压光子场剂量估计不足。事实证明,当硅胶乳房植入体的密度高于水时,治疗计划系统中的剂量准确性就会提高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Modelling of silicone breast implants for radiotherapy treatment planning.

There has been no published work characterizing the attenuation of silicone breast implants in MV energy photon beams. As a result of systematic out of tolerance in-vivo dosimetry results, this report investigates whether the CT Hounsfield Units to electron density curve provides an accurate estimate of attenuation in silicone implants. A CT scan of a silicone breast implant centered on top of WT1 blocks was acquired with simple 6 MV and 10 MV plans created. Dose was calculated using the CT and a collapsed cone algorithm. The predicted dose was compared to doses measured with ionization chamber at 2 points downstream of the implant. Predicted dose from the treatment planning system was 0.9-1.7% lower than measured. The use of a density override on the implant of water (1 g/cm3) improved agreement to less than 1% for all energies and measurement depths. We conclude that the use of CT Hounsfield Units for silicone breast implants leads to an under-estimation of dose in MV photon fields. Dose accuracy has been shown to be improved in the treatment planning system when silicone breast implants have a density override of water.

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来源期刊
Medical Dosimetry
Medical Dosimetry 医学-核医学
CiteScore
2.40
自引率
0.00%
发文量
51
审稿时长
34 days
期刊介绍: Medical Dosimetry, the official journal of the American Association of Medical Dosimetrists, is the key source of information on new developments for the medical dosimetrist. Practical and comprehensive in coverage, the journal features original contributions and review articles by medical dosimetrists, oncologists, physicists, and radiation therapy technologists on clinical applications and techniques of external beam, interstitial, intracavitary and intraluminal irradiation in cancer management. Articles dealing primarily with physics will be reviewed by a specially appointed team of experts in the field.
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