CEUS上的环增强:它在甲状腺实性结节的鉴别诊断中有用吗?

IF 2.5 4区 医学 Q1 ACOUSTICS
Tingting Li, Lijuan Mao, Xi Wang, Cuixian Li, Caihong Dong, Wenqing Wu, Hantao Wang, Qing Lu
{"title":"CEUS上的环增强:它在甲状腺实性结节的鉴别诊断中有用吗?","authors":"Tingting Li, Lijuan Mao, Xi Wang, Cuixian Li, Caihong Dong, Wenqing Wu, Hantao Wang, Qing Lu","doi":"10.1177/01617346241291511","DOIUrl":null,"url":null,"abstract":"<p><p>To investigate the efficiency of contrast-enhanced ultrasound (CEUS) features, particularly ring-enhancement patterns, in the differential diagnosis of thyroid nodules. 302 nodules with CEUS ring-enhancement were retrospectively enrolled, including 135 benign and 167 malignant ones. The ring-enhancement patterns were classified into regular and irregular hyper- or hypo-ring enhancement. Comparative analyses of ultrasound (US) and CEUS features between benign and malignant nodules were performed. The diagnostic performances of the ring-enhancement patterns and Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) were compared in nodules with different sizes. Irregular hypo-ring enhancement was much more common in malignancies than that in benign ones, and it was an independent predictor for thyroid malignant nodules. With irregular hypo-ring enhancement as the diagnostic criteria for malignant nodules, the specificity was higher than that of C-TIRADS (85.2% vs. 75.6%, <i>p</i> = .037) while the AUC was comparable (0.845 vs. 0.803, <i>p</i> = .136) in all nodules. When the nodule size was taken into account, the specificity and AUC were both significantly higher than those of C-TIRADS (92.8% vs. 81.1%, <i>p</i> = .021; 0.907 vs. 0.823, <i>p</i> = .026) in nodules ≥10 mm, which can decrease the unnecessary FNA rate. Irregular hypo-ring enhancement was a valuable CEUS feature for the differential diagnosis of thyroid nodules, especially in nodules ≥10 mm.</p>","PeriodicalId":49401,"journal":{"name":"Ultrasonic Imaging","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ring-Enhancement on CEUS: Is it Useful in the Differential Diagnosis of Solid Thyroid Nodules?\",\"authors\":\"Tingting Li, Lijuan Mao, Xi Wang, Cuixian Li, Caihong Dong, Wenqing Wu, Hantao Wang, Qing Lu\",\"doi\":\"10.1177/01617346241291511\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>To investigate the efficiency of contrast-enhanced ultrasound (CEUS) features, particularly ring-enhancement patterns, in the differential diagnosis of thyroid nodules. 302 nodules with CEUS ring-enhancement were retrospectively enrolled, including 135 benign and 167 malignant ones. The ring-enhancement patterns were classified into regular and irregular hyper- or hypo-ring enhancement. Comparative analyses of ultrasound (US) and CEUS features between benign and malignant nodules were performed. The diagnostic performances of the ring-enhancement patterns and Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) were compared in nodules with different sizes. Irregular hypo-ring enhancement was much more common in malignancies than that in benign ones, and it was an independent predictor for thyroid malignant nodules. With irregular hypo-ring enhancement as the diagnostic criteria for malignant nodules, the specificity was higher than that of C-TIRADS (85.2% vs. 75.6%, <i>p</i> = .037) while the AUC was comparable (0.845 vs. 0.803, <i>p</i> = .136) in all nodules. When the nodule size was taken into account, the specificity and AUC were both significantly higher than those of C-TIRADS (92.8% vs. 81.1%, <i>p</i> = .021; 0.907 vs. 0.823, <i>p</i> = .026) in nodules ≥10 mm, which can decrease the unnecessary FNA rate. Irregular hypo-ring enhancement was a valuable CEUS feature for the differential diagnosis of thyroid nodules, especially in nodules ≥10 mm.</p>\",\"PeriodicalId\":49401,\"journal\":{\"name\":\"Ultrasonic Imaging\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-10-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ultrasonic Imaging\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1177/01617346241291511\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ACOUSTICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ultrasonic Imaging","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1177/01617346241291511","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ACOUSTICS","Score":null,"Total":0}
引用次数: 0

摘要

研究对比增强超声(CEUS)特征,尤其是环状增强模式在甲状腺结节鉴别诊断中的有效性。回顾性收集了302个有CEUS环形增强的结节,其中包括135个良性结节和167个恶性结节。环状增强模式分为规则环状增强和不规则环状增强。对良性和恶性结节的超声(US)和 CEUS 特征进行了比较分析。比较了环状增强模式和中国甲状腺影像报告和数据系统(C-TIRADS)对不同大小结节的诊断性能。不规则低环增强在恶性结节中比在良性结节中更常见,是甲状腺恶性结节的独立预测指标。将不规则低环强化作为恶性结节的诊断标准,其特异性高于 C-TIRADS (85.2% 对 75.6%,p = 0.037),而在所有结节中的 AUC 值相当(0.845 对 0.803,p = 0.136)。如果考虑到结节的大小,对于≥10 毫米的结节,其特异性和 AUC 均明显高于 C-TIRADS(92.8% vs. 81.1%,p = .021;0.907 vs. 0.823,p = .026),这可以降低不必要的 FNA 率。不规则低环强化是鉴别诊断甲状腺结节的一个有价值的 CEUS 特征,尤其是在≥10 毫米的结节中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ring-Enhancement on CEUS: Is it Useful in the Differential Diagnosis of Solid Thyroid Nodules?

To investigate the efficiency of contrast-enhanced ultrasound (CEUS) features, particularly ring-enhancement patterns, in the differential diagnosis of thyroid nodules. 302 nodules with CEUS ring-enhancement were retrospectively enrolled, including 135 benign and 167 malignant ones. The ring-enhancement patterns were classified into regular and irregular hyper- or hypo-ring enhancement. Comparative analyses of ultrasound (US) and CEUS features between benign and malignant nodules were performed. The diagnostic performances of the ring-enhancement patterns and Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) were compared in nodules with different sizes. Irregular hypo-ring enhancement was much more common in malignancies than that in benign ones, and it was an independent predictor for thyroid malignant nodules. With irregular hypo-ring enhancement as the diagnostic criteria for malignant nodules, the specificity was higher than that of C-TIRADS (85.2% vs. 75.6%, p = .037) while the AUC was comparable (0.845 vs. 0.803, p = .136) in all nodules. When the nodule size was taken into account, the specificity and AUC were both significantly higher than those of C-TIRADS (92.8% vs. 81.1%, p = .021; 0.907 vs. 0.823, p = .026) in nodules ≥10 mm, which can decrease the unnecessary FNA rate. Irregular hypo-ring enhancement was a valuable CEUS feature for the differential diagnosis of thyroid nodules, especially in nodules ≥10 mm.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Ultrasonic Imaging
Ultrasonic Imaging 医学-工程:生物医学
CiteScore
5.10
自引率
8.70%
发文量
15
审稿时长
>12 weeks
期刊介绍: Ultrasonic Imaging provides rapid publication for original and exceptional papers concerned with the development and application of ultrasonic-imaging technology. Ultrasonic Imaging publishes articles in the following areas: theoretical and experimental aspects of advanced methods and instrumentation for imaging
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信