术前计算机断层扫描对冠状动脉旁路移植术患者神经系统预后的影响:倾向分数分析

IF 0.7 Q3 Medicine
Mariano Cefarelli, Pietro Giorgio Malvindi, Olimpia Bifulco, Beatrice Buratto, Paolo Berretta, Carlo Zingaro, Filippo Capestro, Michele Danilo Pierri, Jacopo Alfonsi, Alessandro D'Alfonso, Marco Di Eusanio
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引用次数: 0

摘要

导言:神经系统并发症是冠状动脉旁路移植术(CABG)的重大风险。本研究探讨了术前胸部计算机断层扫描(CT)在优化高风险 CABG 患者预后和减少神经系统事件方面的潜在益处:从 2017 年 1 月到 2023 年 6 月,一项对 CABG 患者的回顾性队列研究根据术前胸部 CT 的使用情况进行了分组。多变量分析评估了CT成像与患者特征之间的关联,然后进行倾向匹配分析,以平衡各组患者的术前特征:该研究共纳入了 1786 名患者,其中 435 人接受了术前 CT 检查,1351 人未接受术前 CT 检查。倾向匹配产生了两组均衡的患者,每组 413 人。多变量分析显示,CT 患者年龄较大(71.1 ± 8.9 岁;P = 0.03),肺部疾病发病率较高(19.5%;P = 0.02)。在匹配的 CT 队列中,围手术期脑卒中发生率为 0.7%(与未进行术前 CT [WCT] 队列中的 1.9%相比;P = 0.223),30 天死亡率为 0.2%(与 WCT 队列中的 1.7%相比;P = 0.069)。接受术前 CT 检查的患者主动脉瓷化的发生率更高(6.3% 对 1.5%;P = 0.0003),需要进行无触点主动脉手术的比例更高(20.3% 对 14.5%;P = 0.035):结论:接受 CABG 术前胸部 CT 的患者通常年龄较大,患有全身动脉粥样硬化和肺部疾病。倾向匹配分析表明,这些高危患者的死亡率和围手术期脑卒中发生率较低。这些研究结果支持将胸部 CT 纳入高危患者的术前评估,以便为冠状动脉搭桥手术制定有针对性的策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of preoperative computed tomography scan on neurological outcomes in coronary artery bypass grafting patients: A propensity-score analysis.

Introduction: Neurological complications pose significant risks in coronary artery bypass grafting (CABG). This study explores the potential benefits of preoperative chest computed tomography (CT) in optimizing outcomes and reducing neurological events in high-risk CABG patients.

Methods: From January 2017 to June 2023, a retrospective cohort study of CABG patients categorized groups based on preoperative chest CT use. Multivariate analysis evaluated the associations between CT imaging and patient characteristics, followed by propensity match analysis to balance preoperative features across groups.

Results: The study included 1786 patients, with 435 having undergone preoperative CT and 1351 without. Propensity matching created two well-balanced groups of 413 patients each. At multivariate analysis, CT patients were elderly (71.1 ± 8.9 years; p = 0.03) with a higher incidence of pulmonary disease (19.5%; p < 0.01), peripheral arterial disease (29.2%; p < 0.01), and previous cerebrovascular disease (23.4%; p = 0.02). In the matched CT cohort, the perioperative cerebral stroke rate was 0.7% (vs. 1.9% in without preoperative CT [WCT] cohort; p = 0.223), and the 30-day mortality rate was 0.2% (vs. 1.7% in WCT cohort; p = 0.069). Patients who had a preoperative CT study presented a higher prevalence of porcelain aorta (6.3% vs. 1.5%; p = 0.0003) and required more often a no-touch aorta procedure (20.3% vs. 14.5%; p = 0.035).

Conclusions: Patients undergoing preoperative chest CT before CABG were typically older and had systemic atherosclerosis and pulmonary disease. Propensity-matched analysis indicated low mortality and perioperative cerebral stroke rates in these high-risk patients. These findings support the integration of chest CT into preoperative evaluations for high-risk patients to develop tailored strategies in coronary artery bypass surgery.

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来源期刊
CiteScore
1.30
自引率
0.00%
发文量
78
期刊介绍: The Asian Cardiovascular and Thoracic Annals is an international peer-reviewed journal pertaining to cardiovascular and thoracic medicine. Besides original clinical manuscripts, we welcome research reports, product reviews, reports of new techniques, and findings of special significance to Asia and the Pacific Rim. Case studies that have significant novel original observations, are instructive, include adequate methodological details and provide conclusions. Workshop proceedings, meetings and book reviews, letters to the editor, and meeting announcements are encouraged along with relevant articles from authors.
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