一家三级儿科医院在甲型 H1N1 流感爆发期间对急性坏死性脑炎重症患儿的管理：三例系列病例和文献综述。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-11-11 DOI:10.1055/a-2442-5810

Annalisa D'Eleuterio, Paolo Rufini, Manuela L'Erario, Gabriele Simonini, Carlotta Montagnani, Stefano Ermini, Silvia Ricci, Luca Bartolini, Zaccaria Ricci

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引用次数: 0

摘要

急性坏死性脑病（ANE）是一种严重的神经系统疾病，可通过临床和特定的放射影像学检查确诊。这种病症的医学治疗方法尚不确定，为了最大限度地减少脑损伤和全身炎症，时机的选择可能非常重要。本系列病例描述了在最近的一次流感爆发中，三名因感染甲型 H1N1 流感而继发 ANE 的患者，他们接受了越来越积极的抗炎治疗，但结果却大相径庭。

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Management of Critically Ill Children with Acute Necrotizing Encephalitis during an H1N1 Outbreak in a Tertiary Pediatric Hospital: A Series of Three Cases and Literature Review.

Acute necrotizing encephalopathy (ANE) is a severe neurological condition that is diagnosed clinically and upon specific radiological imaging. Medical treatment of this condition is uncertain, and timing is likely very important to minimize brain damage and systemic inflammation. The present case series describes three patients suffering from ANE secondary to influenza A/H1N1 infection during a recent outbreak, treated with increasingly aggressive anti-inflammatory approach, and with significantly different outcomes.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.