因接触美白霜中的汞而引起的 NELL-1 膜性肾病：两个病例的报告。

IF 2.4 4区医学 Q2 UROLOGY & NEPHROLOGY

Nephrology Pub Date : 2024-12-01 Epub Date: 2024-10-13 DOI:10.1111/nep.14403

Pankaj Jawandhiya, Ankur Gupta

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引用次数: 0

摘要

美容化妆品中含有的汞可导致慢性中毒和膜性肾病（MN）。我们报告了两例由 MN 引起的肾病综合征病例，有证据表明他们在短短几个月内使用了美白霜而导致汞中毒。患者的神经表皮生长因子样 1 [NELL-1]呈阳性。停用化妆品和改良的庞蒂切利疗法改善了这些患者的肾病状态。我们建议，对于 NELL-1 阳性且使用过美容产品的患者，应考虑汞中毒。

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NELL-1 membranous nephropathy due to mercury exposure from fairness cream: Report of two cases.

Mercury contained in beauty-enhancing cosmetics can cause chronic poisoning and membranous nephropathy (MN). We report two cases of nephrotic syndrome caused by MN with evidence of mercury poisoning due to the application of fairness cream in a short duration of a few months. The individuals were positive for neural epidermal growth factor-like 1 [NELL-1]. Discontinuation of the use of cosmetic products and modified Ponticelli regimen improved the nephrotic state in these individuals. We suggest that mercury poisoning should be considered in NELL-1-positive individuals with a history of application of beauty products.

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来源期刊

Nephrology 医学-泌尿学与肾脏学

CiteScore

4.50

自引率

4.00%

发文量

128

审稿时长

4-8 weeks

期刊介绍： Nephrology is published eight times per year by the Asian Pacific Society of Nephrology. It has a special emphasis on the needs of Clinical Nephrologists and those in developing countries. The journal publishes reviews and papers of international interest describing original research concerned with clinical and experimental aspects of nephrology.