成人莫亚莫亚血管病变的诊断和管理:指南建议概述及未来研究方向的确定。

IF 6.3 2区 医学 Q1 CLINICAL NEUROLOGY
Nicola Rifino, Dominique Hervè, Francesco Acerbi, Satoshi Kuroda, Giuseppe Lanzino, Peter Vajkoczy, Anna Bersano
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引用次数: 0

摘要

尽管在了解莫亚莫亚血管病(MMA)的治疗和预后方面取得了进展,但该疾病的几个方面在很大程度上仍不为人所知。特别是缺乏有关 MMA 病史和治疗的证据,这主要是由于现有研究在方法和选择上存在偏差,以及缺乏大型随机前瞻性研究。因此,对 MMA 患者的治疗仍局限于全球少数几个专家中心,而管理往往基于当地的专业知识和可用资源。多年来,人们撰写了一些建议或专家意见,为医生治疗这种疾病提供指导,目的是降低中风复发和长期残疾的风险。然而,由于涉及的文章、方法、专业知识和文献综述的有效方法不同,现有指南和建议之间并不完全一致。对 MMA 的管理缺乏共识可能会使临床医生感到困惑,并突出了一些重要问题和要点。本综合综述论文旨在批判性地研究这三份最新的 MMA 指南,讨论它们之间的异同,并强调 MMA 护理中需要涵盖的空白点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnosis and management of adult Moyamoya angiopathy: An overview of guideline recommendations and identification of future research directions.

Despite the progress made in understanding the management and outcomes of Moyamoya angiopathy (MMA), several aspects of the disease remain largely unknown. In particular, evidence on the disease history and management of MMA is lacking, mainly due to methodological and selection biases in the available studies and the lack of large, randomized prospective studies. Therefore, the care of MMA patients remains limited to a few expert centers worldwide, and management is often based on local expertise and available resources. Over the years, recommendations or expert opinions have been written to provide guidance to physicians in the treatment of this condition with the goal of reducing the risk of stroke recurrence and long-term disability. However, there is no complete agreement between the available guidelines and recommendations due to differences in the articles addressed, methodologies, expertise, and validated approaches to literature review. This lack of consensus on the management of MMA may confuse clinicians and highlight some important issues and points. The aim of this comprehensive review article is to critically examine three recent guidelines and recommendations on MMA, discussing their differences and similarities and highlighting gaps in MMA care that need to be covered.

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来源期刊
International Journal of Stroke
International Journal of Stroke 医学-外周血管病
CiteScore
13.90
自引率
6.00%
发文量
132
审稿时长
6-12 weeks
期刊介绍: The International Journal of Stroke is a welcome addition to the international stroke journal landscape in that it concentrates on the clinical aspects of stroke with basic science contributions in areas of clinical interest. Reviews of current topics are broadly based to encompass not only recent advances of global interest but also those which may be more important in certain regions and the journal regularly features items of news interest from all parts of the world. To facilitate the international nature of the journal, our Associate Editors from Europe, Asia, North America and South America coordinate segments of the journal.
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