治疗疼痛的闭环神经接口：我们的现状如何？

IF 11.7 1区医学 Q1 CELL BIOLOGY

Cell Reports Medicine Pub Date : 2024-10-15 DOI:10.1016/j.xcrm.2024.101662

Jing Wang, Zhe Sage Chen

引用次数: 0

摘要

闭环神经接口和神经调控技术的进步为慢性疼痛提供了一种潜在有效且无成瘾性的治疗方法。这些接口将神经传感器与设备输出连接起来，提供时间上精确的刺激。我们将讨论最先进的神经接口在动物模型和人体试验中治疗疼痛所面临的挑战和发展趋势。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Closed-loop neural interfaces for pain: Where do we stand?

Advances in closed-loop neural interfaces and neuromodulation have offered a potentially effective and non-addictive treatment for chronic pain. These interfaces link neural sensors with device outputs to provide temporally precise stimulation. We discuss challenges and trends of state-of-the-art neural interfaces for treating pain in animal models and human pilot trials.

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来源期刊

Cell Reports Medicine Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

15.00

自引率

1.40%

发文量

231

审稿时长

40 days

期刊介绍： Cell Reports Medicine is an esteemed open-access journal by Cell Press that publishes groundbreaking research in translational and clinical biomedical sciences, influencing human health and medicine. Our journal ensures wide visibility and accessibility, reaching scientists and clinicians across various medical disciplines. We publish original research that spans from intriguing human biology concepts to all aspects of clinical work. We encourage submissions that introduce innovative ideas, forging new paths in clinical research and practice. We also welcome studies that provide vital information, enhancing our understanding of current standards of care in diagnosis, treatment, and prognosis. This encompasses translational studies, clinical trials (including long-term follow-ups), genomics, biomarker discovery, and technological advancements that contribute to diagnostics, treatment, and healthcare. Additionally, studies based on vertebrate model organisms are within the scope of the journal, as long as they directly relate to human health and disease.