在小儿扁桃体切除术中,深喉与清醒拔除喉罩气道对出现谵妄的影响:随机对照试验。

IF 1.1 4区 医学 Q3 ANESTHESIOLOGY
Dhruv Kapoor, Eliza A Tweddle, Luke Baitch
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引用次数: 0

摘要

在全身麻醉后的恢复阶段,幼儿会出现以哭闹不止、知觉障碍和惊跳为特征的谵妄。我们的目的是确定喉罩气道拔除的时间(深度麻醉与清醒状态)是否会影响扁桃体切除术后儿童出现谵妄的发生率。澳大利亚地区医院阿尔伯里沃东加卫生院开展了一项单中心随机对照试验。参加试验的患者年龄在两岁到七岁之间,美国麻醉医师协会身体状况分类为1-2级,在全身麻醉下接受择期扁桃体切除术(带或不带腺样体切除术或扣环植入术)。患者被随机分配在深度麻醉时(在手术室)或苏醒后(在麻醉后护理病房(PACU))摘除喉罩。在睁眼后 5 分钟和 20 分钟测定小儿麻醉后谵妄评分,并记录 PACU 中并发症(咳嗽、呕吐、唾液分泌过多、氧饱和度降低和喉痉挛)的发生频率。62名患者被随机分配到深喉喉罩摘除组,62名患者被随机分配到清醒组。在清醒组和深喉切除组中,分别有 33 人(53%)和 40 人(65%)在 5 分钟内出现谵妄(几率比(OR)为 0.63,95% 置信区间(CI)为 0.30 至 1.29,P = 0.20)。20分钟时,18(29%)对19(31%)名参与者出现谵妄(OR 0.93,95% CI 0.43 至 2.00,P = 0.88)。大多数 PACU 并发症的发生率在清醒组和深部麻醉组之间有较大差异:咳嗽(24% 对 8%)、呕吐(8% 对 0%)、唾液分泌过多(23% 对 8%)和氧饱和度降低(16% 对 0%)。我们发现这两种技术在防止出现谵妄方面没有明显差异。不过,清醒移除术的 PACU 并发症发生率更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effect of deep versus awake removal of the laryngeal mask airway on the incidence of emergence delirium in paediatric tonsillectomy: A randomised controlled trial.

Emergence delirium, characterised by inconsolable crying, perceptual disturbances and thrashing, occurs in young children during the recovery phase from general anaesthesia. Our aim was to determine whether timing of laryngeal mask airway removal (deeply anaesthetised versus awake) influenced the incidence of emergence delirium in children after tonsillectomy. A single-centre, randomised controlled trial was conducted at Albury Wodonga Health, a regional hospital in Australia. Included patients were two to seven years old, American Society of Anesthesiologists physical status classification 1-2, undergoing elective tonsillectomy (with or without adenoidectomy or grommet insertion) under general anaesthesia. Patients were randomised to have their laryngeal mask removed whilst deeply anaesthetised (in the operating theatre) or after awakening (in the post-anaesthesia care unit (PACU)). Pediatric Anesthesia Emergence Delirium score was determined at 5 and 20 min after eye opening, and frequency of complications (cough, vomiting, excessive salivation, oxygen desaturation and laryngospasm) in the PACU were recorded. Sixty-two patients were randomised to deep laryngeal mask removal and 62 to awake. In the awake versus deep groups, 33 (53%) versus 40 (65%) participants had emergence delirium at 5 min (odds ratio (OR) 0.63, 95% confidence interval (CI) 0.30 to 1.29, P = 0.20). At 20 min, 18 (29%) vs. 19 (31%) participants had emergence delirium (OR 0.93, 95% CI 0.43 to 2.00, P = 0.88). A greater incidence of most PACU complications was observed in the awake versus deep group; cough (24% vs. 8%), vomiting (8% vs. 0%), excessive salivation (23% vs. 8%) and oxygen desaturation (16% vs. 0%). We found no significant difference between the two techniques in terms of preventing emergence delirium. However, other PACU complications were more frequent with awake removal.

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来源期刊
CiteScore
2.70
自引率
13.30%
发文量
150
审稿时长
3 months
期刊介绍: Anaesthesia and Intensive Care is an international journal publishing timely, peer reviewed articles that have educational value and scientific merit for clinicians and researchers associated with anaesthesia, intensive care medicine, and pain medicine.
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