无金属可见光诱导的乙烯基硼酸化/硅烷化吡啶基反应

IF 4.6 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Chemistry Frontiers Pub Date : 2024-10-22 DOI:10.1039/d4qo01702a

Yiting Zhou, Bin Liu

{"title":"无金属可见光诱导的乙烯基硼酸化/硅烷化吡啶基反应","authors":"Yiting Zhou, Bin Liu","doi":"10.1039/d4qo01702a","DOIUrl":null,"url":null,"abstract":"We present a metal-free and gentle three-component reaction involving vinylarenes, NHC-BH3 complexes, hydrosilanes, and 4-cyanopyridine. This versatile reaction encompasses a broad scope, encompassing over 40 examples of vinylarenes, NHC-BH3 complexes, and hydrosilanes, leading to the synthesis of diverse β-pyridinyl boranes and β-pyridinyl silanes. Furthermore, we demonstrate the potential of this methodology by functionalizing pharmaceutical molecules, showcasing its practical applications","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metal Free Visible-Light-Induced Borylative/Silylative Pyridylation of Vinylarenes\",\"authors\":\"Yiting Zhou, Bin Liu\",\"doi\":\"10.1039/d4qo01702a\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We present a metal-free and gentle three-component reaction involving vinylarenes, NHC-BH3 complexes, hydrosilanes, and 4-cyanopyridine. This versatile reaction encompasses a broad scope, encompassing over 40 examples of vinylarenes, NHC-BH3 complexes, and hydrosilanes, leading to the synthesis of diverse β-pyridinyl boranes and β-pyridinyl silanes. Furthermore, we demonstrate the potential of this methodology by functionalizing pharmaceutical molecules, showcasing its practical applications\",\"PeriodicalId\":97,\"journal\":{\"name\":\"Organic Chemistry Frontiers\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-10-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Organic Chemistry Frontiers\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1039/d4qo01702a\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic Chemistry Frontiers","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4qo01702a","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}

引用次数: 0

摘要

我们介绍了一种涉及乙烯基醚、NHC-BH3 配合物、氢硅烷和 4-氰基吡啶的无金属温和三组分反应。这种多用途反应范围广泛，涵盖了 40 多个乙烯基烯烃、NHC-BH3 复合物和氢硅烷的实例，从而合成了多种 β-吡啶基硼烷和 β-吡啶基硅烷。此外，我们还通过对药物分子进行功能化，展示了这一方法的潜力及其实际应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Metal Free Visible-Light-Induced Borylative/Silylative Pyridylation of Vinylarenes

We present a metal-free and gentle three-component reaction involving vinylarenes, NHC-BH3 complexes, hydrosilanes, and 4-cyanopyridine. This versatile reaction encompasses a broad scope, encompassing over 40 examples of vinylarenes, NHC-BH3 complexes, and hydrosilanes, leading to the synthesis of diverse β-pyridinyl boranes and β-pyridinyl silanes. Furthermore, we demonstrate the potential of this methodology by functionalizing pharmaceutical molecules, showcasing its practical applications

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.