钯催化的两种不同烯烃的烃基交叉偶联反应

IF 4.6 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Chemistry Frontiers Pub Date : 2024-10-22 DOI:10.1039/d4qo01312c

Hanmin Huang, Yi Chen, Jianing Wu, Yongzheng Ding

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引用次数: 0

摘要

过渡金属催化的烯烃烃化反应已被广泛研究，然而，发生在两个烯烃之间的烃化反应在很大程度上尚未被探索。在此，我们报告了一种钯催化的烃化交叉偶联反应，通过两种不同的烯烃生成结构多样的 β-酮醛代用品，这些代用品可以很容易地转化为不同类型的杂环，包括吡唑、异噁唑和嘧啶。

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Palladium-catalyzed hydrocarbonylative cross-coupling with two different alkenes

Transition-metal-catalyzed hydrocarbonylation of alkenes has been widely studied, however, the hydrocarbonylation reaction that took place between two alkenes has been largely unexplored. Herein, we report a palladium-catalyzed hydrocarbonylative cross-coupling with two different alkenes to produce structurally diverse β-ketoaldehyde surrogates, which can be easily converted to different types of heterocycles including pyrazole, isoxazole and pyrimidine.

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来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.