甲状旁腺切除术后 PTH 水平和动力学的变化

IF 2.7 3区医学 Q1 SURGERY

American journal of surgery Pub Date : 2024-10-10 DOI:10.1016/j.amjsurg.2024.116010

Claire E. Graves MD, Michael J. Campbell MD

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引用次数: 0

摘要

术中甲状旁腺激素（IOPTH）是一种外科辅助手段，用于在甲状旁腺切除术中 "实时 "评估剩余甲状旁腺的功能。甲状旁腺降解动力学受抽血时间、患者特征和疾病表型的影响。对这些多重因素的细致了解有助于甲状旁腺外科医生解释 IOPTH 结果。本文总结了有关 PTH 动力学的最新文献，重点介绍了如何在甲状旁腺手术中将这些知识应用于临床。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Variation in PTH levels and kinetics after parathyroidectomy

Intraoperative parathyroid hormone (IOPTH) is a surgical adjunct used to assess function of remaining parathyroid glands in “real-time” during parathyroidectomy. Parathyroid degradation kinetics are affected by timing of blood draws, patient characteristics, and disease phenotype. A nuanced understanding of these multiple factors can help parathyroid surgeons interpret IOPTH results. This article summarizes recent literature on PTH kinetics with a focus on how to apply this knowledge clinically during parathyroid surgery.

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来源期刊

American journal of surgery 医学-外科

CiteScore

5.00

自引率

6.70%

发文量

570

审稿时长

56 days

期刊介绍： The American Journal of Surgery® is a peer-reviewed journal designed for the general surgeon who performs abdominal, cancer, vascular, head and neck, breast, colorectal, and other forms of surgery. AJS is the official journal of 7 major surgical societies* and publishes their official papers as well as independently submitted clinical studies, editorials, reviews, brief reports, correspondence and book reviews.