N. V. Koronevskiy, O. A. Inozemtseva, B. V. Sergeeva, M. A. Popova, A. A. Andreev, S. A. Sergeev
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Optimization of the Mineralization Process of Polycaprolactone Fibers with Vaterite Microparticles
Optimization of the process of mineralization of polycaprolactone fibers with vaterite microparticles by varying the concentrations of the working solutions of salts, calcium chloride and sodium carbonate, is proposed. The optimum parameters of mineralization of polycaprolactone fibers with calcium carbonate particles in the vaterite polymorphic modification are found. The effect of the concentrations of the working solutions of the salts and time of ultrasonic treatment on the monodispersity of CaCO3 microparticles present in the composition of the synthesized coating is studied. The concentrations of the working solutions of the salts are varied from 0.25 to 1 mol and the time of US treatment is varied from 30 to 90 s. The obtained tissue-engineered scaffolds can find application in regenerative medicine and for local and prolonged release of drugs. For their successful use for medical purposes, special requirements must be met, namely, the minimum possible polydispersity and the existence of calcium carbonate microparticles in the vaterite polymorphic modification.
期刊介绍：
Inorganic Materials: Applied Research contains translations of research articles devoted to applied aspects of inorganic materials. Best articles are selected from four Russian periodicals: Materialovedenie, Perspektivnye Materialy, Fizika i Khimiya Obrabotki Materialov, and Voprosy Materialovedeniya and translated into English. The journal reports recent achievements in materials science: physical and chemical bases of materials science; effects of synergism in composite materials; computer simulations; creation of new materials (including carbon-based materials and ceramics, semiconductors, superconductors, composite materials, polymers, materials for nuclear engineering, materials for aircraft and space engineering, materials for quantum electronics, materials for electronics and optoelectronics, materials for nuclear and thermonuclear power engineering, radiation-hardened materials, materials for use in medicine, etc.); analytical techniques; structure–property relationships; nanostructures and nanotechnologies; advanced technologies; use of hydrogen in structural materials; and economic and environmental issues. The journal also considers engineering issues of materials processing with plasma, high-gradient crystallization, laser technology, and ultrasonic technology. Currently the journal does not accept direct submissions, but submissions to one of the source journals is possible.
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