贝赫切特综合征患者全髋关节和全膝关节置换术后并发症的风险。

IF 2 Q2 ORTHOPEDICS
Philip P Ratnasamy, Fortunay Diatta, Omar Allam, Martin Kauke-Navarro, Jonathan N Grauer
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引用次数: 0

摘要

背景:贝赫切特综合征(BS)是一种多系统自身免疫性疾病,对全髋关节置换术(THA)和全膝关节置换术(TKA)术后效果的影响尚不明确。本研究评估了BS患者围手术期不良事件的相对风险:这项回顾性队列研究使用了全国性大型行政数据库 PearlDiver M157Ortho 数据集。根据患者的年龄、性别、Elixhauser 综合征指数评分和所实施的手术(THA 或 TKA),确定了患有 BS 的全髋关节置换术和全髋关节置换术患者,并与未患有 BS 的患者进行了 1:4 的配对。通过多变量分析确定并比较了90天不良事件的发生率。对翻修手术的5年存活率进行评估,并通过对数秩检验进行比较:结果:经过配对,确定了282例THA/TKA患者患有BS,并与1127例未患有BS的患者进行了比较。多变量分析显示,与无 BS 患者相比,BS 患者发生任何(赔率 [OR] 2.16,P < 0.0001)、严重(OR 1.78,P = 0.0051)和轻微(OR 2.39,P < 0.0001)不良事件的风险更高。翻修手术的5年存活率无明显差异(P = 0.3):结论:接受THA或TKA手术的BS患者术后90天不良事件明显增多。结论:接受THA或TKA手术的BS患者术后90天不良事件明显增多,这些发现强调了对接受关节置换术的BS患者进行优化围手术期管理的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Risk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients.

Background: Behcet syndrome (BS), a multisystem autoimmune disorder, has unclear effects on outcomes after total hip arthroplasty (THA) and total knee arthroplasty (TKA). This study assessed the relative risk of perioperative adverse events in patients with BS.

Methods: This retrospective cohort study used the PearlDiver M157Ortho data set, a large national administrative database. Total hip arthroplasty and TKA patients with BS were identified and matched 1:4 to those without BS based on patient age, sex, Elixhauser Comorbidity Index scores, and procedure performed (THA or TKA). The incidence of 90-day adverse events was determined and compared by multivariate analysis. 5-year survival to revision surgeries was assessed and compared with the log-rank test.

Results: After matching, 282 THA/TKA patients with BS were identified and compared with 1127 without BS. On multivariate analysis, patients with BS were at independently greater risk of aggregated any (odds ratio [OR] 2.16, P < 0.0001), serious (OR 1.78, P = 0.0051), and minor (OR 2.39, P < 0.0001) adverse events compared with those without BS. No significant difference was observed in 5-year survival to revision surgery (P = 0.3).

Conclusions: Patients with BS undergoing THA or TKA experienced markedly greater 90-day postoperative adverse events. The findings underscore the need for optimized perioperative management for patients with BS undergoing arthroplasty.

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来源期刊
CiteScore
2.60
自引率
6.70%
发文量
282
审稿时长
8 weeks
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