南澳大利亚州发生的一起涉及恶嗪、苯并咪唑类阿片（硝氮类）和新型苯并二氮杂卓的多种药物中毒事件。

IF 1.7 4区医学 Q2 EMERGENCY MEDICINE

Emergency Medicine Australasia Pub Date : 2024-10-10 DOI:10.1111/1742-6723.14512

Emma Partridge, Peter Stockham, Michaela Kenneally, Andrew Luong, Chris Kostakis, Sam Alfred

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引用次数: 0

摘要

目的重点研究在一组疑似吸食海洛因的患者中检测到的异丙嗪和硝唑仑以及苯并咪唑类阿片（硝氮类）和其他新型苯并二氮杂卓：方法：从加入澳大利亚新药网络系统的患者中收集去身份化的临床和分析数据：2023 年 12 月，三名成人因疑似吸食海洛因后出现镇静症状而就诊于急诊室。对血液样本进行的毒理学分析发现了恶嗪、质子他嗪、美托尼他嗪、溴唑仑和硝唑仑。当地卫生部门随后发出警报：这是在澳大利亚首次发现使用羟嗪和硝西泮的迹象。这些结果表明，对药物进行分析确认的毒物监测计划在监测非法药物使用方面非常有价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A cluster of multi-drug intoxications involving xylazine, benzimidazole opioids (nitazenes) and novel benzodiazepines in South Australia.

Objective: To highlight the detection of xylazine and nitrazolam in conjunction with benzimidazole opioids (nitazenes) and other novel benzodiazepines in a cluster of patients after putative heroin use.

Methods: Deidentified clinical and analytical data were gathered from patients enrolled in the Emerging Drugs Network of Australia system.

Results: In December 2023, three adults presented to the ED with sedation following putative use of heroin. Toxicological analysis of blood samples identified xylazine, protonitazene, metonitazene, bromazolam and nitrazolam. Local health authorities subsequently issued an alert.

Conclusion: This is the first signal of xylazine and nitrazolam use in Australia. These results demonstrate toxico-surveillance programmes with analytical confirmation of drugs are invaluable in monitoring illicit drug use.

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来源期刊

Emergency Medicine Australasia 医学-急救医学

CiteScore

3.70

自引率

13.00%

发文量

217

审稿时长

6-12 weeks

期刊介绍： Emergency Medicine Australasia is the official journal of the Australasian College for Emergency Medicine (ACEM) and the Australasian Society for Emergency Medicine (ASEM), and publishes original articles dealing with all aspects of clinical practice, research, education and experiences in emergency medicine. Original articles are published under the following sections: Original Research, Paediatric Emergency Medicine, Disaster Medicine, Education and Training, Ethics, International Emergency Medicine, Management and Quality, Medicolegal Matters, Prehospital Care, Public Health, Rural and Remote Care, Technology, Toxicology and Trauma. Accepted papers become the copyright of the journal.